Un-Complicating Cholesterol and Cardiovascular Disease | Josh Wageman - E407

Low Carb MD Podcast

Drs. Brian Lenzkes & Tro Kalayjian

Diet, Mental Health, Lowcarb, Nutrition, Keto, Brianlenzkes, Health & Fitness, Jasonfung, Doctortro, Intermittentfasting, Trokalayjian, Medicine, Meganramos

4.8 • 1.2K Ratings

🗓️ 11 August 2025

⏱️ 63 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Josh Wageman is a board-certified Clinical Lipid Specialist dedicated to transforming the way we understand and treat heart disease. With a deep expertise in cholesterol, metabolic health, and cardiovascular risk, he helps patients cut through the noise and take control of their health using evidence-based, personalized strategies. Known for translating complex science into actionable steps, Josh is passionate about prevention and proving that heart disease doesn’t have to be inevitable.

In this episode, Dr. Brian and Josh talk about…

(00:00) Intro
(00:32) Josh’s interesting and varied career path
(04:31) Understanding cardiovascular disease in a nutshell
(8:15) Understanding lipoproteins
(10:10) Why lipids are controversial and what we can all agree on
(12:28) LDL and HDL particles
(19:35) Endurance athletes and coronary calcium
(29:54) Atherosclerosis, carnivore, and gut dysbiosis
(39:46) Advanced lipid panels
(40:29) Statins and LDL
(44:13) Pros and cons of statins
(49:54) Supplements that may be helpful for cardiovascular health
(52:44) Rapping and singing about lipids and heart health
(55:09) Science and faith; physical health and spiritual health
(01:02:25) Outro

For more information, please see the links below. Thank you for listening!

Links:

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

Josh Wageman:

Dr. Brian Lenzkes:

Website: https://arizonametabolichealth.com/
Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

Website: https://www.doctortro.com/
Twitter: https://twitter.com/DoctorTro
Instagram: https://www.instagram.com/doctortro/

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together.

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://doctortro.com/community/

Transcript

Click on a timestamp to play from that location

0:00.0	Welcome to the low-carb MD podcast.
0:03.2	No one is beyond help.
0:04.9	No one is beyond hope.
0:07.2	Nothing said on the low-carb-m-D podcast is medical advice.
0:11.3	Please consult your own doctor before making any lifestyle changes.
0:20.5	Hello and welcome back to the low-carb MD podcast. Today we have a smart kid here.
0:25.1	Yeah, we usually don't let Ivy Leaguers here, but we're going to make an exception since you went to Yale.
0:29.7	We'll let you come in and educate us a little bit. A youth pastor, you've done it all, youth pastor,
0:35.1	physical therapy, and you're focused on cholesterol and making it so that people can understand it. So how did you come down this road? How do the Lord lead you down this road?
0:44.7	Yeah, I have been so blessed to have many opportunities and many circuitous situations that have led me here.
0:57.6	And, you know, I've done the youth ministries at our church outside of Boise, Idaho for the last 13 years.
0:58.8	That's actually interesting because that's the one thing I didn't go to school for, but it
1:03.5	was just where God wanted me.
1:05.4	And that's a cool thing there.
1:06.6	But basically, the first time I went to grad school, I went for physical therapy school.
1:12.5	And God uses even adverse situations to catalyze our paths and what we're supposed to do when we grow up.
1:19.6	And so I got really, really sick, actually.
1:21.5	And I was a Division I track athlete and I got really sick.
1:26.0	And no one could really figure out what was going on.
1:28.6	And so I was like, well, you know, this stuff's kind of interesting, even though it's miserable.
1:32.4	So let me see if I can figure it out.
1:34.6	So I got me falling in love with biochemistry and endocrinology.
	...

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