Two Pathogenic Fungi Crossed the Species Barrier—Can Now Infect Humans
Facts Matter
The Epoch Times
4.9 • 1.3K Ratings
🗓️ 29 January 2026
⏱️ 15 minutes
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Summary
The premise for “The Last of Us,” both the video game and the HBO hit series, centers around the survival of two people navigating a post-apocalyptic wasteland after a mutated fungus infected most of the world’s population, turning victims into mindless zombies.
At first glance, it appears like just another interesting take on the zombie genre.
But believe it or not, the game is actually based on a real-life genus of fungus called cordyceps, which survives by infecting insects, hijacking their immune systems, and turning them into vessels that the fungus then controls. The fungus parasite then guides the insect body to a desirable location where it can spread to other hosts.
While the concept that a fungus can turn humans into mindless zombies might seem far-fetched, there is already mounting concern within the scientific community that mutating strains of fungi are rapidly evolving in response to changing climate, to the point where they are beginning to present a real threat to human health.
In recent years, several genera of fungi (which had previously not been a problem) are now able to infect humans.
Let’s go through the current state of pathogenic fungi.
Transcript
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| 0:00.0 | The premise for The Last of Us, both the video game as well as the HBO hit series, |
| 0:05.5 | it centers around the survival of two people who are navigating a post-apocalyptic wasteland |
| 0:11.2 | after a mutated fungus infected most of the world's population and basically turn them into |
| 0:17.5 | infected, mindless zombies. Now, at first glance, it appears just like any other |
| 0:23.4 | interesting take on the zombie genre. But believe it or not, the game is actually based on a real-life |
| 0:29.8 | genus of fungus called cortisps, which survive by infecting insects, hijacking their immune systems, |
| 0:37.0 | and turning them into vessels that the fungus |
| 0:39.5 | then controls, sort of like a Japanese anime mex suit. The fungus parasite then guides the |
| 0:46.8 | insect's body to a desirable location where they can then spread to other hosts. If you ever |
| 0:52.9 | want to see some creepy but absolutely fascinating nature videos online, |
| 0:58.0 | just search for cortisps take over insects through mind control on YouTube. |
| 1:02.8 | It basically looks like the insects are alive and well |
| 1:05.6 | until the fungus makes them bite down into the ground. |
| 1:09.5 | It's called a death bite and they're basically |
| 1:11.2 | stuck there forever. And then a giant parasite sprouts out their back, sucks the life out of them, |
| 1:18.8 | blooms itself, and releases thousands of spores in order to infect more insects. It's brutal to |
| 1:25.9 | watch. But getting back to The Last of Us, while the concept of |
| 1:30.0 | a fungus like that, being able to turn humans into mindless zombies might still seem far-fetched, |
| 1:36.6 | there is already mounting concern within the scientific community that actually studies these things, |
| 1:42.0 | that mutating strains of fungi are rapidly evolving in a response |
| 1:46.4 | to a warmer climate to the point where they're actually beginning to present a real threat |
| 1:51.2 | to human health. |
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