TWiV 990: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 11 March 2023

⏱️ 29 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update Dr. Griffin discusses confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era, the effectiveness of maternal Influenza vaccination in Peru, characteristics and predictors of persistent symptoms post-COVID-19 in children and young people, parental nonadherence to health policy recommendations for prevention of COVID-19 transmission among children, community-onset bacterial coinfection in children critically ill with SARS-CoV-2 infection, bivalent booster effectiveness against severe COVID-19 outcomes in Finland, viral kinetics of sequential SARS-CoV-2 infections, risk of COVID-19 associated pulmonary aspergillosis based on corticosteroid duration in intensive care patients, immunomodulators for severe COVID19 in transplant patients: do they increase the risk of secondary infection, long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population, cardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection, one-year adverse outcomes among us adults with Post–COVID-19 condition vs those without COVID-19 in a large commercial insurance database, and long-term gastrointestinal outcomes of COVID-19. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Confronting the evolution and expansion of anti-vaccine activism (The Lancet) Effectiveness of maternal influenza vaccination in Peru (OFID) Characteristics and predictors of persistent symptoms post-COVID-19 (BMJ) Parental nonadherence to health policy recommendations for prevention of COVID-19 (JAMA) Community-onset bacterial coinfection in children ill with SARS-CoV-2 infection (OFID) Bivalent booster effectiveness against severe COVID-19 outcomes (medRxiv) Viral kinetics of sequential SARS-CoV-2 infections (medRxiv) Risk of COVID-19 associated pulmonary aspergillosis based on corticosteroid duration in ICU patients (OFID) Immunomodulators for severe COVID-19 in transplant patients (TID) Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population (eClinicalMedicine) Cardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection (BMJ) One year adverse outcomes among US adults with post COVID-19 condition vs those without COVID-19 (JAMA) Long-term gastrointestinal outcomes of COVID-19 (Nature) Contribute to our ASTMH fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 990 Don’t crush Paxlovid (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.3	From micro TV, this is Twiv, this week in virology episode 990 recorded on March 8th, 2023.
0:21.0	I'm Vincent Drakken yellow and you're listening to the podcast all about viruses.
0:25.6	Joining me tonight from New York, Daniel Griffin.
0:30.5	Hello, everyone. Daniel has winter over. Is the respiratory virus season over yet?
0:36.0	You know, R.C. flew some of them where we're on the down slope, which is nice.
0:42.3	You know, COVID will get to, but let me hit right into the quotation.
0:49.1	So we beat on boats against the current, born back, ceaselessly into the past.
0:54.5	And that's, that's by one of my favorite authors, F. Scott Fitzgerald, from one of my favorite
1:00.0	books, The Great Gatsby. And I have to say, this has been a challenging week where history seems
1:04.8	to be in the midst of being rewritten. And I feel like it is like Groundhog Day, but in a bad way,
1:10.8	or again, stepping right in the same puddles and told that water is actually not wet.
1:15.2	So let's start with the viewpoint, confronting the evolution and expansion of anti-vaccine activism
1:21.6	in the USA in the COVID-19 era, published in The Lancet. It's an article by several of our friends,
1:27.1	including one of our directors at Paracetzo.org, is Peter Hotez. It's interesting and informative.
1:33.6	It's a quick read. So this is not a big thing to bite off. But it points out that how over the past two
1:39.6	decades, anti-vaccine activism in the USA has evolved from a fringe subculture into an
1:45.5	increasingly well-organized networked movement with important repercussions for public health. The COVID-19
1:52.2	pandemic has exacerbated this evolution and magnified the reach of vaccine misinformation.
1:57.7	There are several recommendations on how to address the spread of the problem in the article,
2:01.1	but it's worth looking at. I think this making our jobs more and more difficult as we face
2:08.1	the victims of this coordinated misinformation campaign. Influenza, the article,
	...

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