TWiV 966: 1918 influenza with Jeffery Taubenberger

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 23 December 2022

⏱️ 112 minutes

🔗️ Recording | iTunes | RSS

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Summary

Vincent travels to the NIH campus to speak with Jeffery Taubenberger about his career, the 1918 influenza pandemic, deciphering the genome sequence of the virus from tissues of disease victims and using it to rescue infectious virus. Host: Vincent Racaniello Guest: Jeffery Taubenberger Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Influenza 1918 pandemic questions answered (Sci Transl Med) Reconstructed 1918 influenza virus (Science) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is TWIV, this week in virology, a special episode recorded on October 20th,
0:18.7	2022. I'm Vincent Racken-Yellow and you're listening to the podcast all about viruses.
0:24.8	Today, I'm on the campus of the National Institute of Health and my guest, who I've been wanting to speak with
0:33.4	a long time, is Jeffrey Taubenberger. Welcome to TWIV. Thank you, Vincent. Appreciate the invitation.
0:39.1	My pleasure. I'm here for ID Week, so I thought I would try and see if you were available, so I'm glad
0:44.9	it worked out. Yeah, me too. It's great to try. And I just wanted to mention, in case Brett is listening,
0:50.9	Brett Jager, right? Or Jagger? Like Mick Jagger, right? Yeah. I met him at a restaurant yesterday, and
0:58.8	we'd had never met, and he recognized me because like everyone else, TWIV has gotten pretty wide,
1:05.7	so we were recognized among scientists, and I told him I was coming to talk to you, and he told me
1:09.9	he trained with you. He did. Years ago. Yeah, he did his MDPHD, his PhD in the NIH Oxford Cambridge
1:17.6	program, so I was the NIH mentor and Paul DeGuard in the UK was his Cambridge mentor. Excellent.
1:23.7	Excellent. All right, so I wanted to talk with you about 1918 influenza, and I think it's timely
1:29.5	that people coming out of a big pandemic, we talk about what we learned from that, and I think most
1:35.4	of our listeners don't know much about it. So let's tackle that, but I wanted to first understand
1:41.3	how you got interested in influenza. It's a kind of a crazy story, how I got interested in influenza.
1:48.3	So let me back up a little bit. I did MDPHD, and my, where was that? In the medical college of
1:54.3	Virginia, in Richmond, Virginia, and my research interest was hematopoietic stem cell development,
2:00.5	specifically looking at how hematopoietic stem cells from the bone marrow would commit to the
2:05.8	lymphocyte lineage to become T cells through the thymus, order to become B cells.
2:09.5	I ended up doing a pathology residency, and I did that here at NIH through the Cancer Institute,
2:17.2	and then stayed on as a staff pathologist, continued my research on stem cell development.
	...

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