TWiV 961: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 10 December 2022

⏱️ 28 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update Dr. Griffin discusses Mpox (formerly monkeypox) in women: epidemiological features and clinical characteristics of mpox cases in Spain, April to November 2022, triage of patients with Ebola virus disease, SARS-CoV-2 serology and self-reported infection among adults, serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal marker of natural infection in vaccinated individuals, sensitivity of anti-SARS-CoV-2 nucleocapsid protein antibody for breakthrough infections during the epidemic of the Omicron variants, effect of wearing glasses on risk of infection with SARS-CoV-2 in the community, and data-driven identification of post-acute SARS-CoV-2 infection subphenotypes. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Mpox in women: Epidemiological features and clinical characteristics of cases (Eurosurveillance) Triage of patients with Ebola virus disease (The Lancet) SARS-CoV-2 serology and self-reported infection among adults (CDC) Serological markers of SARS-CoV-2 infection (JID) Sensitivity of anti-SARS-CoV-2 nucleocapsid protein antibody (Journal of infection) Effect of wearing glasses on risk of infection with SARS-CoV-2 in the community (JAMA) Paxlovid patient eligbiliity screening checklist (FDA) Data-driven identification of post-acute SARS-CoV-2 infection subphenotypes (Nature) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 961 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is Twiv, this week in virology, episode 961 recorded on December 8th, 2022.
0:21.0	I'm Vincent Racken Yellow and you're listening to the podcast all about viruses. Joining me today
0:27.6	from Uganda, Daniel Griffin. Hello everyone. I'm recording this as I told Vincent outdoors using my
0:36.7	iPhone for a light. I'm on the banks of the source of the Nile, so the eastern part of Uganda here.
0:46.2	So hopefully hopefully the quality will be fine. There's a bit of a storm going on. So if you hear
0:52.0	crashing, that's okay. That's just lightning and thunder. That's the city that you're in, Daniel.
0:57.0	It's called ginger. Okay. Check that out. All right. Well, let me start. Let's get right into
1:02.1	this. Education is the most powerful weapon which you can use to change the world. And that's
1:07.6	Nelson Mandela. So we'll continue on our focus on education. And I'm hoping to share a bit of
1:14.0	information today. I'm going to start off with measles. Yes, this week I am adding measles.
1:19.4	So people may be aware of the current outbreak in Ohio. I was going to say here, but I'm not in Ohio.
1:25.3	We're up to over 50 cases. Last I checked it was 50, 9, 20 individuals hospitalized. I just want
1:33.2	to say they are all unvaccinated. And actually the majority of the cases are in children less than
1:39.9	two years of age. As I mentioned, I'm recording this from Uganda. And at the foundation, international
1:46.7	medical relief of children clinic. So femur clinic on Monday, I saw a two year old boy who came in
1:52.6	with fever, runny nose, feeling irritable. And that's an understatement, just miserable. Iaritation,
2:00.3	cough, poor appetite. This was going on for about five days, just really miserable, according to
2:07.5	the mother. Initially there was no rash. Then after about five days, he started to develop a rash
2:14.4	on his face, spread down the neck and onto the chest. And we see him. He's got this rash.
2:19.2	Lungs were clear. Child just incredibly miserable. Odd, white, grain-like lesions inside the mouth
2:26.0	on the sides, testing, including blood smear for malaria parasites was negative. That's a little
	...

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