TWiV 908: COVID-19 clinical update #118 with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 11 June 2022

⏱️ 46 minutes

🔗️ Recording | iTunes | RSS

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Summary

In COVID-19 clinical update #118, Dr. Griffin discusses management of hair loss after infection, FDA announcements on vaccine schedule and recommendations, Moderna announcement on bivalent booster candidate, association between vaccination and infection during pregnancy, population-level implications of Israel’s booster campaign, PAXLOVID outcomes during recent infection surge, efficacy and safety of Tixagevimab-cilgavimab, diagnostic accuracy of infection by canines, efficacy of colchicine in hospitalized patients, and factors associated with hospital readmission. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Management of hair loss after infection (NIH) FDA announces vaccine schedule meeting (FDA) FDA advisory committee recommends NOVAVAX vaccine (Novavax) Moderna announces bivalent booster candidate (Moderna) Association of vaccination and infection during pregnancy (JAMA) Implications of Israeli booster campaign (Science Translational Medicine) PAXLOVID patient eligibility screening checklist (FDA) Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA) PAXLOVID outcomes during infection surge (Research Square) Efficacy and safety of Tixagevimab–cilgavimab (The Lancet) Diagnostic accuracy of infection by canines (PLOS ONE) Efficacy of colchicine in hospitalized patients (Nature) Factors associated with readmission (IDSA) Contribute to FIMRC fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 908 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From microbe TV, this is TWIV, this week in virology, episode 908 recorded on June 9th, 2022.
0:21.5	I'm Vincent Racken Yellow and you're listening to the podcast all about viruses joining me today from
0:27.9	New York, Daniel Griffin. Hello, everyone. Daniel, how many pandemics do we have right now in the
0:33.7	world? You know, you know, that's actually an interesting question, right? So we still have the
0:38.3	HIV pandemic going on that never ended. We've got the COVID-19 pandemic that has not ended.
0:47.2	I don't know if I'm going to say monkey pox is a pandemic. Everyone's very excited about it.
0:52.1	What about hepatitis B and hepatitis C? They're pandemic. That's interesting, right?
0:57.1	That we don't think of them as, you know, but they are. They are pandemic. And you know,
1:01.9	the number one cause of cancer on the planet, solid organ cancer is hepatitis B virus. So yeah.
1:09.2	W H O never declared SARS-1 a pandemic, right? 25, 26 countries, 8,000 cases, wasn't enough.
1:18.5	Yeah. So monkey pox can't be a pandemic if that wasn't.
1:22.0	Anyway, that's an interesting. I mean, obviously it's, it's a human thing and it,
1:28.8	there's no biological basis for it, right? Yeah. Calling something a pandemic and I just
1:33.2	bunch of people get in the room and they're like, so what do you think? All right. Well, let's get
1:36.8	right to it. Ignorance is the parent of fear. And that's Herman Melville from Moby Dick. It's,
1:43.6	I can say one of my favorite books, but I like to say the first 125 pages and then it drags.
1:48.9	Even for a man who enjoys, you know, nautical jargon. But all right, let's start with our update.
1:55.7	Novavax Tuesday. So the FDA's vaccines and related biological products advisory committee voted yes
2:03.7	in response to the question. Do the benefits of Novavax's vaccine given as a two dose primary
2:09.9	series, that way it's risks in people aged 18 and older based on available evidence. So 21 members
2:17.0	voted yes, one abstained, none voted no. And they go on to say that we have reviewed the data
	...

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