TWiV 897: COVID-19 clinical update #113 with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 7 May 2022

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

In COVID-19 clinical update #113, Dr. Griffin discusses tocilizumab use in hospitalized Patients, IL-6 inhibitors and mortality, Baricitinib in hospitalized patients, post-infection neurological sequelae, comparative effectiveness of Pfizer and Moderna vaccines, phase 2/3 study of Paxlovid, infection relapse following Paxlovid, pre-hospital administration of Remdesivir, and hospitalization with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Timing of Tocilizumab Use in Hospitalized Patients (NIH) Interleukin-6 inhibitors reduce mortality (European Journal of Internal Medicine) Treatment Effect of Baricitinib on Hospitalized Patients (IDSA) Post Infection Neurological Sequelae (Res Square) Comparative Effectiveness of Pfizer and Moderna Vaccines (Nature Commun) Results from Phase 2/3 Study of Paxlovid (Pfizer) Infection Relapse Following Suppression by Paxlovid (Res Square) Update on Paxlovid Usage (FDA) Availability and Use of Treatments in Outpatients (CDC) Pre-Hospital Administration of Remdesivir (IDSA) Remdesivir and three other drugs for Hospitalized Patients (Lancet) Guidelines on Usage of Anticoagulants (Am Soc Hematol) Different Variants Hospitalization and Morality (Res Square) Contribute to FIMRIC fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 897 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

Click on a timestamp to play from that location

0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.5	From micro TV, this is twiv this week in virology, episode eight hundred and ninety seven recorded on May
0:19.2	5th, 2022. I'm Vincent Racken yellow and you're listening to the podcast all about viruses. Joining me
0:27.0	today from New York, Daniel Griffin. Hello, everyone. And this is update number one hundred and thirteen.
0:36.0	Uh, our case is going up, Daniel recorded on Cinco de Mayo. Oh, that's right. And you know,
0:42.5	yesterday, what yesterday was, don't you? May the fourth be with you. Oh, you're with it. You're
0:47.5	good. Try to keep up. All right. So let's, let's go. Let's start with the quotation. We have a lot
0:53.7	to cover today. It's a recession when your neighbor loses his job. It's a depression when you
0:59.0	lose a yours. And that's Harry Truman. Actually, my dad's a great Harry Truman fan and, and it's just
1:05.8	reading an article about him recently. And so that sort of got me thinking about Harry Truman.
1:10.9	But I think that's one of the tough things about so much in life here is that, you know, for a lot
1:16.2	of people, it's been somewhat abstract. People that have been able to keep themselves safe.
1:20.4	Before a lot of people, this has been really personal and tragic. I was speaking to a social worker
1:25.8	today that does a lot of counseling for elders who have lost, you know, a lot of people close to
1:31.6	them sort of hardest hit parts of our population, the vulnerable, the elderly, social economic,
1:39.1	different race. So been a tough time for a lot of people. But okay, let's where are we headed?
1:45.2	We have a schedule of FDA meetings for June. So there's a lot of exciting things. They're going
1:50.0	to be happening in June. June 7th, the FDA intends to convene to discuss an E-way request for it's
1:58.2	going to be the VRB PAC to discuss an E-way request for a COVID-19 vaccine manufactured by NovaVax
2:06.3	to prevent COVID-19 in individuals 18 years of age and older. I know we've had a lot of individuals.
2:12.6	Actually, a lot of our listeners have been asking when is this going to happen. So if there's
2:17.1	folks out there still waiting for this, June 7th, June 8th, 21 and 22, the FDA held dates for the
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Vincent Racaniello, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Vincent Racaniello and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.