TWiV 1335: TldR, bacterial hot rods and nullifying norovirus

This Week in Virology

Vincent Racaniello

Virus, Pathogen, Infection, Medicine, Microbe, Virology, Infectious, Science & Medicine, Vincent, Twiv, Microbiology, Racaniello

4.8 • 2.2K Ratings

🗓️ 28 June 2026

⏱️ 116 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV explains research showing how temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling, and that IgA antibody is necessary and sufficient to prevent norovirus infection in mice. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Fred Murphy passes away (X) US has lost its hold on measles elimination (CIDRAP) What’s in the genetic code of America’s measles outbreaks (ProPublica) Did Pete Hegseth single-handedly raise the R₀ of flu? (Inside Medicine) Fred Murphy’s Virus Images and Foundations of Virology (UTMB) Temperate phages and RNA-guided flagellar remodelling (Nat Micro) Eukaryotic RNA guided system (Nature) IgA prevents norovirus infection in mice (Sci Transl Med) Craig Wilen’s letter to TWiV (TWiV 492) Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – APod June 26: Milky Way Urban Style Rich – Your birth order affects your future, but not for the reason you think; Dr. McCoy Jolene – Bakteriopolis paper and site Vincent – The Claude Shutdown Is a Total Sh*tshow Listener Pick Martin – Ancient text charred by Vesuvius read for first time in 2,000 years Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This week in Virology, the podcast about viruses, the kind that make you sick.
0:10.1	From MicrobTV, this is Twiv this week in Virology.
0:15.2	Episode 1335 recorded on June 26th, 2026.
0:23.4	That's it.
0:24.5	June's over.
0:25.2	Summer's over.
0:26.6	I'm Vincent Rackeniello and you're listening to the podcast.
0:29.8	All About Viruses.
0:32.0	Joining me today from College Station, Texas, Jolene Ramsey.
0:37.5	Hello there. It's a nice, hot, Texas, Jolene Ramsey. Hello there.
0:39.0	It's a nice, hot, sunny day here in Texas.
0:44.0	We have 90 degrees Fahrenheit and 32 degrees Celsius.
0:48.0	It's pretty humid.
0:49.0	It rained earlier in the week, and it's still 59% humidity.
0:54.1	Here in New York, it's 28C and cloudy.
0:56.7	It's very pleasant.
0:58.9	Also joining us from Madison, New Jersey, Brianne Barker.
1:02.8	Hi, great to be here.
1:05.1	It's very similar as one might expect in Madison, New Jersey, 83 Fahrenheit 29C, and pretty cloudy.
1:13.4	And from Austin, Texas, Rich Condit.
1:17.5	Howdy?
1:18.4	I got about what, logically, about what Jolene has, my new cool Apple Watch says it's 92 out, which is consistent with my experience, more or less.
	...

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