TWiV 1329: How HIV-1 goes nuclear

This Week in Virology

Vincent Racaniello

Vincent, Pathogen, Medicine, Microbiology, Infectious, Virology, Virus, Infection, Science & Medicine, Microbe, Racaniello, Twiv

4.8 • 2.2K Ratings

🗓️ 7 June 2026

⏱️ 111 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV explains research showing limited transmission of cervid prions to nonhuman primates, and the finding that cone-shaped HIV-1 capsids are transported through intact nuclear pores. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Ebola outbreak news (ECDC, WHO) NSF research grants on hold (Nature) Transmission of cervid prions to nonhuman primates (Sci Adv) Cone-shaped HIV-1 capsids transported intact through nuclear pore (Cell) HIV-1 reproduction video (Janet Iwasa) Letters read on TWiV 1329 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – What We Need to do NEXT Re: OMB Rule Alan – Metallic Realms, by Lincoln Michel Vincent – TWiV 1: West Nile Virus Listener Picks Mark – How the Library of Congress packed 250 years of U.S. history into a vial the size of a quarter Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This week in Virology, the podcast about viruses, the kind that make you sick.
0:10.3	From MicrobTV, this is Twiv, this week in Virology, episode 1329 recorded on June 5th, 2026.
0:21.6	I'm Vincent Rackeniello, and you're listening to the podcast, All About Viruses.
0:28.3	Joining me today from Madison, New Jersey, Briand Barker.
0:32.3	Hi, it's great to be here.
0:35.1	In Madison, it is absolutely gorgeous right now.
0:38.8	It is 88 Fahrenheit and sunny.
0:42.7	And just a really lovely day.
0:44.3	I think it's going to be pretty similar to this all weekend.
0:47.3	And I'm ready for that.
0:50.5	Also joining us from Western Massachusetts, Alan Dove.
0:54.3	Good to be here. And here in Western Mass, it's 87 Fahrenheit 31C, but it's a dry heat.
1:00.7	Humidity is 26%. A little nice little breeze and clear skies. It's supposed to be like this through tomorrow.
1:08.0	And then we've got some thunderstorms rolling in Saturday night.
1:12.2	32C and cloudy here in Chelsea. I was just out for 10 minutes. My assistant comes in.
1:18.9	She said, are you recording yet? I said, no, not for 45 minutes. She said, there's a free donut at
1:23.5	crispy cream. We're going to come and get one for me too. So I said, I don't want a donut, but you can have mine. So today is National Donut Day. Oh. And Krispy Cream is giving away a free donut if you just go up and ask them. So we got one and I gave her mine because I don't want a donut. But it's very nice out. It's very crowded here because the Madison Square Garden, which is two blocks from the incubator, is hosting a basketball game tonight.
1:48.4	They are selling Nick T-shirts right in front of the incubator.
1:52.5	So I thought if I put a table next to it selling Twiv T-shirts, would anyone buy it?
1:58.9	And my assistant said, not if it doesn't have a sports theme.
2:02.9	What if you made it in Nick's colors?
2:05.5	Yeah, it could.
	...

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