TWiV 1312: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Twiv, Medicine, Microbe, Infection, Infectious, Virology, Virus, Microbiology, Pathogen, Racaniello, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 11 April 2026

⏱️ 45 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC’s decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. coli illness in raw cheese, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, clinical practice guidelines for treating COVID-19, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, if the nasal microbiome modulates COVID-19 disease severity, reviews the use of steroid, antibiotics, anticoagulants and IVIG for treating COVID-19 including long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode State public health labs step up as CDC pauses testing for various pathogens, including rabies, mpox (CIDRAP) Infectious Diseases Laboratories : Test Directory (CDC) Kennedy rewrites the rule for membership on US vaccine advisory panel (Reuters) Advisory Committee on Immunization Practices (ACIP): ACIP charter (CDC) Quick takes: More E coli tied to raw cheese, drug-resistant Shigella in UK, TB funds for Sudan (CIDRAP) Voluntary Recall (FDA) E. coli Outbreak Linked to Raw Dairy (CDC: E.coli Infection (Escherichia coli)) We 100% disagree with the FDA’s false “possible link”, and extreme allegations (RawFarm USA) Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis(Neurology) US Scientists Sequence 1,000 Genomes From Measles, a Disease Long Eliminated With Vaccines (KFF HealthNews) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) UtahMeasles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19 (CID) 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Baricitinib vs. Tocilizumab (CID) ImmunobridgingAnalysis of Pemivibart for the Treatment of COVID-19 – A Therapeutic Gap for the Immune Compromised Remains (OFID) PEMGARDA® is authorized for use in certain moderately to severely immunocompromised patients to help prevent COVID-19 (Pemgarda) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Association of nasopharyngeal Dolosigranulum pigrum and Corynebacterium species with post-acute sequelae of SARS-CoV-2 in a longitudinal cohort (Microbiology Spectrum) The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge: a retrospective follow up study (Clinical and Experimental Medicine) Intravenous immunoglobulin treatment for long COVID: a case report of clinical and immunological findings (LANCET: Infectious Diseases) Management of Orthostatic Hypotension (JAMA: Internal Medicine) Reaching out to US house representative Letters read on TWiV 1312 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:11.0	From MicrobTV, this is Twiv. This week in Virology, episode 1312 recorded on April, I almost said August, April 9th, 2026.
0:24.6	I'm Vincent Rackeniello and you're listening to the podcast, All About Viruses.
0:30.1	Joining me today from New York, Daniel Griffin.
0:34.1	Hello, everyone.
0:36.0	You know, I should know the blue bow tie by now.
0:38.5	It's not Friday, it's Thursday.
0:40.5	Okay, so is it a preon?
0:43.4	So this is a tough one, and maybe they'll need to zoom in.
0:48.1	But it's actually, I think, one of the original infectious-awareable bow ties.
0:52.6	It's streptococci. So you really have to zoom in to see it.
0:57.8	So it's very subtle. It just looks like, oh, what a nice bow tie. And then you're like, wait a second.
1:04.2	So a little diplo cox eye there. All right, let's jump in. We got a lot. We got a lot to do today.
1:11.8	You're down in Princeton, I understand.
1:14.2	I was.
1:14.5	I got back and I'm home and right here sitting in my little office studio, getting ready to do Twiv.
1:21.8	Okay.
1:22.8	Well, we're starting.
1:23.8	We are revising our textbook.
1:26.3	It was our last meeting. And the seventh, what is it, the sixth edition will be out next year. Okay. And you, hopefully you took out all that basic science and focused more on like keeping your hair dry and character and stuff. Vitamin A. Yeah. Okay.
1:45.3	There is no shame in not knowing.
1:47.8	The problem arises when irrational thought and attendant behavior fill the vacuum left
	...

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