TWiV 1273: Myocarditis and mimicry

This Week in Virology

Vincent Racaniello

Virus, Science & Medicine, Microbe, Twiv, Racaniello, Infectious, Pathogen, Vincent, Virology, Infection, Medicine, Microbiology

4.8 • 2.2K Ratings

🗓️ 28 December 2025

⏱️ 118 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA restriction system of the host by mimicking B form DNA. Hosts: Vincent Racaniello and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2026 Understanding mRNA vaccine-associated myocarditis (Sci Transl Med) T7 protein overcomes DNA restriction of host (J Mol Biol) Structure of T7 protein that mimics DNA (Mol Cell) Letters read on TWiV 1283 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Jolene – Book series Dinosaur Therapy, Dinosaur Philosophy, & Dinosaur Friendship Vincent – One Plus One Equals One: Symbiosis and the evolution of complex life by John Archibald Listener Picks Terry – Arcadia by Tom Stoppard Greg – Charctic Interactive Sea Ice Graph | National Snow and Ice Data Center Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:10.2	From MicrowTV, this is Twib. This week in Virology, episode 1283, recorded on December 26, 2025.
0:22.3	I'm Vincent Rackeniello.
0:24.0	You're listening to the podcast, All About Viruses.
0:27.9	Joining me today from College Station, Texas, Jolene Ramsey.
0:33.1	Howdy, Vincent?
0:34.5	Sounds like you have something in your throat.
0:37.9	Yeah, I have a little cold. You know, just the sore throat, sniffles, which I think
0:44.8	I got it, immune 100. You know, I travel all over the world and I'm fine. Then I do something
0:51.0	at the incubator. Yeah, well.
0:54.5	It's like traffic accidents.
0:56.8	They say that you're most likely to get in an accident within like two or 25 miles of home
1:02.7	because you let your guard down.
1:04.5	Yeah, that's true.
1:06.6	Well, here in New York area, it's minus 2.
1:11.6	And starting at 6 p.m., we're supposed to get 8 to 9 inches of snow.
1:16.3	So I stayed home for that and for the common cold.
1:22.9	You've got the real winter over there with your winter viruses.
1:27.3	Here in College Station, it is 26 degrees Celsius and 78 Fahrenheit.
1:33.7	It's a very pleasant day outside.
1:36.5	Feels like late summer.
1:39.6	When I go out, it hurts.
	...

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