TWiV 1273: EBV and lupus have not escaped our notice

This Week in Virology

Vincent Racaniello

Microbe, Infection, Twiv, Vincent, Virus, Pathogen, Science & Medicine, Virology, Infectious, Microbiology, Racaniello, Medicine

4.8 • 2.2K Ratings

🗓️ 23 November 2025

⏱️ 98 minutes

🔗️ Recording | iTunes | RSS

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Summary

TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator CDC revives debunked ‘link’ between childhood vaccines and autism (npr) A structure for deoxyribose nucleic acid (Nature pdf) Three Papers, Three Lessons (Am J Resp Crit Care Med) Discovery of Double Helix (Crick Papers) Jim Watson was blinded by DNA (NY Times) What Rosalind Franklin contributed (Nature) EBV reprograms autoreactive B-cells in lupus (Sci Transl Med) EBV and the making of lupus (Sci Transl Med) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Virus snowflakes Kathy – When “Physic(k)s Lost Its ‘k’ and other Language Quarks Vincent – The Peripheral by William Gibson Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This week in Virology, the podcast about viruses, the kind that make you sick.
0:10.4	From Microbte TV, this is Twiv.
0:13.2	This week in Virology, episode 1273, recorded on November 21st, 2025.
0:22.8	I'm Vincent Rackeniello, and you're listening to the podcast All About Viruses.
0:28.4	Joining me today from Ann Arbor, Michigan, Kathy Spindler.
0:32.5	Hi, everybody.
0:33.4	Here in Ann Arbor, it's 51 Fahrenheit, which is 10 Celsius, white, puffy clouds, blue sky, and a light wind.
0:43.1	Chelsea, New York, it's 11C and cloudy.
0:47.0	Also joining us from Madison, New Jersey, Brianne Barker.
0:50.8	Hi, great to see you all.
0:53.1	In Madison, New Jersey, it is also 51 Fahrenheit, 10C, and also cloudy.
1:00.6	We have got great papers for you today, but first, if you enjoy these paper discussions, you can learn from them.
1:08.8	They're sometimes fun also. Well, for us, it's a lot of fun.
1:12.1	Maybe for you too.
1:13.4	We'd love your support.
1:15.2	Go to microbe.tv slash contribute.
1:17.2	Why do we want your support?
1:19.0	Because we don't do ads to pay for these programs,
1:21.7	and so we depend on you.
1:23.8	I decided a long time ago I didn't want ads.
1:26.8	Okay.
1:27.5	There's a great,
	...

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