TWiV 1213: Secrets of HepB cccDNA

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 27 April 2025

⏱️ 125 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection. Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Committee of experts to counter vaccine misinformation (Science) NSF Director resigns (Science) Dependence of vaccine immune response on gut microbiome (Cell Host Microbe) Nucleosome switch primes HepB replication (Cell) Letters read on TWiV 1212 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Wild chimpanzees filmed by scientists bonding over alcoholic fruit Rich – Malcolm Gladwell Revisionist History “The Joe Rogan Intervention” Vincent – Measles Misinformation Is on the Rise — and Americans Are Hearing It, Survey Finds Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected] Content in this podcast should not be construed as medical advice.

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:10.1	From MicrobTV, this is Twiv.
0:13.5	This Week in Virology episode 1213 recorded on the 25th of April, 2025.
0:23.7	I'm Vincent Rackeniello, and you're listening to the podcast, All About Viruses.
0:29.3	Joining me today from Montreal, Canada, Angela Mingarelli.
0:34.5	Hello, everyone. It's good to be back.
0:36.9	It's actually pretty warm here today. Spring has finally come. Last week, it snowed, but today it is 61F or 16C. I, for the first time, did not wear a coat to the lab today. That was exciting.
0:52.5	Yeah, it's really nice. I wore a coat, a winter coat. I have a thermal
0:57.2	shirt on still, but here it is, because I'm crazy, I just can't break with it. It's 24C. It's really warm.
1:07.1	24? Yeah. So I don't know what that is. Is that like 80 or something? I don't know. That's like rich weather. That's 80ish, yeah. So I don't know what that is. Is that like 80 or something?
1:11.2	I don't need to know.
1:12.0	That's like Ridge weather.
1:13.3	That's 80-ish, yeah.
1:14.8	Oops, I haven't been introduced.
1:16.3	Sorry.
1:17.2	So, joining us from Austin, Texas, Ridge Condit.
1:22.3	Yeah, it happens every now and then.
1:24.1	You wind up auto-introducing yourself.
1:27.1	Okay.
1:28.0	It's okay. Hi, Okay. It's okay.
1:28.4	Hi, everybody.
1:29.8	It's 85 degrees here in Austin, Texas.
	...

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