TWiV 1148: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 14 September 2024

⏱️ 45 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin dives into “pandemic potential” viruses isolated from farmed fur animals, how the mRNA and pox vectored vaccines against mpox spar against each other, how telehealth does managing mpox, and if prophylactic use of the anti-RSV monoclonal for infants is cost-effective before reviewing the recent statistics on SARS-CoV-2 infection, if viral load correlates to one vaccination status, where to find PEMGARDA, does administration of molnupiravir reduce symptoms in the vaccinated, when to use convalescent plasma, how molnupiravirs treatment leads to better outcomes 3 and 6 months after treatment, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against SARS-CoV-2 does protect against long COVID, and if SARS-CoV-2 during Omicron alters ones’ micriobiota. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Lending you the viruses in my fur (Nature) mRNA or vaccinia based mpox vaccine (Cell) Virtual outpatient management of mpox (OFID) NYC: mpox vaccination finder (NYC) Vaccine, mpox/COVID-19 near you (NYC) Expensive or not expensive anti-RSV monoclonal therapy for infants (American Academy of Pediatrics) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Association of vaccination and SARS-CoV-2 viral load phase 3 (JID) IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Early phase of SARs-CoV-2 infection (COVID.gov) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir outcomes 3 and 6 months after treatment (LANCET Infectious Diseases) Antivirals and post-COVID-19 conditions (LANCET Infectious Disease) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID following infection with Omicron: oral microbiota changes(American Journal of Medicine) Letters read on TWiV 1148 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This Week in Virology, the Podcast About Viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive this weekend virology, episode 1148, recorded on September 12,
0:21.0	2024.
0:22.0	I'm Vincent Dracken-yellow and you're listening to the
0:24.8	podcast all about viruses. Joining me today from New York, Daniel Griffin.
0:31.2	Hello everyone.
0:33.6	Trying to, I see on your bow tie, there's spikes.
0:36.6	Okay, there's some virus on your bow tie,
0:38.4	but I can't see it very close.
0:39.7	Actually, it's interesting, if you were to zoom in, this is actually my fungal bow tie.
0:45.2	Oh my gosh. So yeah so this is like a close up of the
0:48.7	canidia and there's little spores and okay and the nice thing is you could sort of wear it
0:54.4	different ways so you can actually end up with it you know other you know so this is like
0:58.8	a bow tie you can bring with you when you travel and depending on how you put it on
1:02.2	it's got a lot of red and blue or a lot of green.
1:05.0	So.
1:06.0	Right. Yeah, I'm reviewing today just coincidentally after putting this on I was reviewing fungal therapeutics and resistant genes and
1:16.8	ergostoral and you know the kino candons and yeah so but let's get right into it and actually I guess speaking about
1:27.6	red and green quote from F Scott Fitzgerald from the Great Gatsby.
1:34.0	So we beat on boats against the current,
1:37.0	born back ceaselessly into the past.
1:40.0	I remember that very much.
	...

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