TWiV 1134: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 27 July 2024

⏱️ 37 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses Merck’s RSV preventative monoclonal antibody Clesrovimab before reviewing the recent statistics on SARS-CoV-2 infection, if previous SARS-COV-2 infections predict the outcome of subsequent infections, if using COVID rapid diagnostic tests is cost effective, if the protein based vaccine NVX-CoV2327 elicits a durable immune response, if combination treatment of vaccine and antiviral drugs effectively protect against hospitalization, where to find PEMGARDA, what do when healthcare workers succumb to SARS-CoV-2 infection, and how COVID-19 may alter the cognitive trajectories of older patients. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Clesrovimab, RSV preventative monoclonal antibody for infants (Merck) COVID-19 national trend (CDC) COVID-19 deaths (CDC) Characterizing SARS-CoV-2 reinfections and long COVID (Communications Medicine) Cost-effectiveness of COVID rapid diagnostic tests (PLoS Medicine) NVX-CoV2373 against pre-Delta and Delta strains of COVID-19 little evidence of waning immune response (CID) Combined Protection of Vaccination and Nirmatrelvir-Ritonavir Against Hospitalization(CID) Pemgarda infusion center locator (Pemgarda) Respiratory virus guidance (CDC) Early phase of SARS-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Cognitive trajectories in older survivors of COVID-19 up to 2.5 years post-infection(Nature Aging) Contribute to our Floating Doctors fundraiser Letters read on TWiV 1134 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This Week in Virology, the Podcast About Viruses, the kind that make you sick.
0:07.0	From Micrope TV, this is Twive, this week in Virology, episode 1134, recorded on July 24,
0:20.0	24, 2024. I'm Vincent Rachanello and you're listening to the podcast all about viruses.
0:28.0	Joining me today from New York, Daniel Griffin.
0:32.0	Hello everyone.
0:33.0	What you got on your tie, Daniel?
0:35.0	Today is my fungus bow ties.
0:38.0	There's conidia, there's spores, all kinds of good fungal stuff.
0:43.2	Yeah, I came down here to have my glass of water and the one that was here was kind of
0:48.2	slimy and I was thinking I will end up, you know, not just having it on my bow tie but so you have a Twive mug Daniel I have I have several
0:56.0	that's usually how I start my day okay good all right let's jump right into it because
1:02.2	I'm gonna try to keep this short because you know we're recording on Wednesday night because well probably after this well when this drops I may actually be done.
1:12.6	We'll have to see.
1:13.7	But I'm starting a 200-mile sailing race
1:16.0	that starts at the Statue of Liberty,
1:18.4	and then goes all the way out around Montauk.
1:21.4	It's like 105 miles open Atlantic before we then drop back into the Long Island
1:26.3	Sound.
1:27.3	Wow, how long is that going to take?
1:30.8	That's the question, isn't it? So, last year we did it in 40 hours.
1:36.0	Started off really fast and then got hit by a squall and then there was some doldrums.
1:42.0	But yeah, we'll see how it goes this year
	...

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