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This Week in Virology

TWiV 1106: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.82.2K Ratings

🗓️ 20 April 2024

⏱️ 44 minutes

🧾️ Download transcript

Summary

In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles before addressing results of Pfizer’s phase 3 RSV vaccine clinical trial for adults under 60, RSV, influenza and SARS-CoV-2 circulation, differences between rural and urban communities dealing with SARS-CoV-2 infections, the latest statistics on influenza and COVID-19 circulation, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how long COVID affects the brain and associates with an increase in allergic incidents as well as if post SARS-CoV-2 infected patients are unable to exercise or have functional limitations. For more information about this body of work, listen to TWiV 1088. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Measles tracking (CDC) Influenza risk factors for potential severe outcomes (OFID) COVID-19 national trend (CDC) Does SARS-CoV-2 infection influence sperm quality (Scientific Reports) Spring COVID-19 booster recommendations (CIDRAP) Older adult spring booster available (CDC) Advisory committee for immunization practices slides (CDC) Advisory committee for immunization practices spring 2024 COVID-19 boosters (CDC) Slide 19 (CDC) EUA for pemgarda (FDA) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (IDSociety) Nirmatrelvir for vaccinated or unvaccinated COVID-19 patients (NEJM) Nirmatrelvir/ritonavir vs. remdesivir for treatment of high risk outpatients (Therapeutic Advances in Infectious Disease) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Outpatient treatment with concomitant vaccine-boosted convalescent plasma (mBio) Updated respiratory virus guidances (CDC) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID evidence based review TWiV shout out (TWiV 1088) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1106 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0

This Week in Virology, the Podcast About Viruses, the kind that make you sick.

0:07.0

From Micope TV, this is Twive this week in Vyrology.

0:15.0

Episode 1106 recorded on April 17, 2024.

0:20.0

I'm Vincent Rachagnello and you're listening to the podcast all about viruses.

0:25.0

Joining me today from New York, Daniel Griffin.

0:30.0

Hello everyone.

0:31.0

You know I can never guess what you've got on your tie.

0:34.4

I guess you have to wait till you cycle through all of them.

0:37.8

You know and then that'll be a test, that'll be a memory test.

0:40.6

But this one's a little tough and I'm pretty sure that I have never

0:43.5

worn this on a microbe TV recorded cast YouTube whatever any of the productions.

0:53.5

This is actually, it's actually more of a disease bow tie.

0:56.6

It's hepatitis, and these are inflamed

1:00.7

hepatocytes. Yeah, I think you were that before. You said. and so I know how many I'm going to have to learn. You know I have about a hundred

1:13.8

bow ties. Oh my gosh all with viruses? It's a variation I've got climate change

1:20.4

I've got sailboats I've got echocerosites I've got sailboats I've got ectoparasites I've got viruses I've got

1:25.9

spirokeats yeah I've got quite the range all right well if you didn't wear a tie, I wouldn't have anything to ask you.

1:35.0

I'd have to ask something else.

1:37.0

We'd have to talk about science.

1:38.0

Imagine that.

1:39.0

Yes.

1:40.0

All right, well, let's jump into it.

...

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