TWiV 1084: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 3 February 2024

⏱️ 44 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses the safety of the prefusion RSV vaccine, if high or moderate dose of the quadrivalent influenza vaccine is better for protection against hospitalization, summarizes the new WHO COVID guidelines, revisits how to prevent pathogen transmission in healthcare setting, the under use of COVID oral antiviral and what occurs in persistently SARS-CoV-2 infected cells in culture after antiviral treatment, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how inflammatory markers change correlate with death when in ICU and if cognitive slowing is part of long COVID-19. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Do you want a job in healthcare? (JAMA) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Efficacy and safety of RSV vaccine after 2 seasons (CID) High vs moderate dose of quadrivalent influenza vaccine (CMI) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) WHO COVID guidance (WHO) Thoughts on COVID guidance (CIDRAP) Update on how to prevent pathogen transmission in healthcare settings (CDC) Underuse of antiviral drugs against COVID-19 (MMWR) Revisiting tissue culture cells persistently infected following antiviral therapy (bioRxiv) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Changes in inflammatory markers and death correlation when in ICU (Cytokine) Long COVID & cognitive slowing? (eClinicalMedicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1084 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This Week in Virology, the podcast about viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive, this week in Vyrology, episode 1084, recorded on January 31st, 2024.
0:24.6	I'm Vincent Dracken-yellow and you're listening to the podcast all about viruses.
0:29.6	Joining me today from New York. Daniel Griffin.
0:33.4	Hello everyone.
0:35.6	What's on the bow tie tonight, Daniel?
0:37.5	This is my anthrax bow tie.
0:40.8	Yeah, I couldn't tell what it was from the distance.
0:45.0	It's an artist, it's an artist rendition, so.
0:48.0	Artist's rendition.
0:50.0	This bound to be wrong, then, right?
0:52.0	It's not quite as obvious as the Ebola, you know,
0:54.8	right outside where you're recording right now, but.
0:57.7	1084, wasn't there a book by Haruki Murakami? Oh,
1:03.0	1084?
1:04.0	I do not know.
1:05.0	Let's see, 10804, Haruki Murakami.
1:10.0	Oh, it's, it's IQ 84.
1:12.0	Not 1084. Okay, that's close enough. We'll take it.
1:16.0	Yep.
1:17.0	All right, well, we got a lot to cover today.
1:19.0	So let me start with the quotation.
	...

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