TWiV 1082: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Racaniello, Virus, Virology, Infection, Microbe, Infectious, Medicine, Microbiology, Science & Medicine, Vincent, Twiv, Pathogen

4.8 • 2.2K Ratings

🗓️ 27 January 2024

⏱️ 54 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, before discussing viral transmission to adults in healthcare setting, the recently EUA approved protein based COBREVAX vaccine, reviews quarantine guidelines, the use of simnotrelivr for mild to moderate COVID-19, how viral RNA may persist in your cell culture dish following antiviral therapy, continues to dispel the myth of viral rebound, how to pay for Paxlovid, , when to use steroids and the benefits of convalescent plasma, how Paxlovid may prevent long COVID and how complement dysfunction may lead to thromboinflammation during long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Articles and graphs cited in TWIV CU 1080 Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Transmission in healthcare setting (CID) COBREVAX EUA (Texas Children’s Hospital) Quarantine/isolation guidelines (CDC) Simnotrelvir for mild to moderate disease in adults (NEJM) Are your tissue culture cells persistently infected following antiviral therapy (bioRxiv) Structural biology of antivirals for SARS-CoV-2 (Signal Tranduction and Targeted Therapy) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Remdesivir for immunocompromised during variant waves (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Patients, experts, Congress…..long COVID oh my! (CIDRAP) Does paxlovid prevent long COVID? (CIDRAP) Persistent complement with thromboinflammation in long COVID (Science) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1082 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

Transcript

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0:00.0	This Week in Vyrology, the podcast about viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive, this weekend virology. Episode 1082,
0:18.0	recorded on January 25, 2024. I'm Vincent Dracken-yellow and you're listening to the podcast
0:27.0	All About Viruses. Joining me today here in New York at the incubator Daniel Griffin.
0:34.0	Hello everyone.
0:36.0	All right Daniel what's with the tuxedo we said we were going to be casual here.
0:41.0	You didn't you didn't get the memo. Well well tonight is is Burns
0:45.6	night so for any of this Scots in the audience this is a celebration of
0:51.1	Rabi Burns famous for Old Lang Zion, a Nobel Laureate poet of Scotland and
0:59.0	after I record I will be going with my daughter Daisy to celebrate Burns Night. We will be
1:05.6	enjoying some wee drafts of Scotch. We'll be reciting poems singing Rabi Burns
1:12.1	songs and I will be enjoying some haggis.
1:17.0	So you need you have to wear a tux to this?
1:19.0	Well this particular event I mean this is a very formal occasion.
1:21.0	So how many people are going to this event?
1:23.4	I think it'll be about a hundred or so yeah. And how do these people get selected?
1:28.1	You just you sign up. You sign up okay. It's and it'll be a mix of you can wear a a standard Western
1:35.4	Tuxedo which Tuxedo Park New York City right where the home of the
1:39.5	Tuxedo or there you're allowed to wear a kilt.
1:43.0	So what you have is a standard Western.
1:46.0	Standard Western. And you tied the bow tie yourself, I see.
1:49.0	Yeah, I just learned to do that.
	...

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