TWiV 1080: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 20 January 2024

⏱️ 34 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US before discussing vaccine effectiveness in children and adolescents, how the pandemic impacted the socioemotional development of infants and toddlers, continues to dispel the myth of viral rebound, how to pay for Paxlovid, reviews quarantine guidelines, when to use steroids and the benefits of convalescent plasma, examines the role of immune aberrations in long COVID and how vaccination may protect against developing long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend(CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Remember when COVID was bad? (Wired) Children and adolescents hospitalized with SARI (Pediatrics) COVID-19 vaccines are effective for adolescents (Pediatrics) Vaccine effectiveness against long COVID in children (Pediatrics) Infant and toddler socioemotional development in the pandemic (JAMA) Quarantine/isolation guidelines (CDC) Should I take Paxlovid? (NY Times) What is this about Paxlovid rebound? (CDC) Rebound is NOT the early inflammatory phase (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) T cell dysregulation inflammation and uncoordinated adaptive immune response, Long COVID oh my (Nat Imm) Vaccine effectiveness against long COVID (CIDRAP) Prevention of long COVID by vaccines (Antimicrobial-stewardship and healthcare) Sex and gender relationship with long COVID (Eurosurveillance) Are all vaccines equal in preventing Long COVID? (Lancet) Vaccine naïve individuals, Long COVID and vaccination (medRxiv) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1080 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This Week in Virology, the Podcast About Viruses, the kind that make you sick. From Microbe TV, this is Twive, this week in Vyrology, episode 1080, recorded on January 17,
0:20.0	2024.
0:22.0	I'm Vincent Rachagnello and you're listening to the podcast all about
0:25.8	viruses joining me today from South America, Daniel Griffin.
0:32.2	Hello everyone yeah basically America, Daniel Griffin.
0:33.2	Hello everyone.
0:34.5	Yeah, basically I'm about 20 miles north of Venezuela,
0:37.9	so that's, yeah, I'm a bit south,
0:40.5	and I guess we're recording this pretty late in my time zone at the moment, but let's get into it because people will be listening to this.
0:48.5	Well, I guess, what is it, East Coast right after midnight and then everyone else adjusted accordingly.
0:54.7	So I'm going to start off with a quotation.
0:56.8	I'm having a little bit of a break so I've been reading the book Dune, so my quotation will
1:01.3	come from Frank Herbert.
1:04.0	The beginning of knowledge is the discovery of something we do not understand.
1:10.3	And I sort of like that.
1:11.0	I mean, it made me think of science. It's you know that humility of going into the
1:16.2	unknown and and learning right? I mean that's that's what I think this is all about.
1:21.2	So we will jump right into RSV. We were a little
1:25.2	worried. I was a little worried. I'll share that we might see one of those little
1:29.0	double dips where RSV starts to go down and then we see another.
1:33.4	And so we saw that second peak and we're hoping in the next week or two,
1:38.3	we really come off that high level of RSV.
	...

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