TWiV 1074: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 30 December 2023

⏱️ 46 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses the outcomes of SARS-CoV-2, influenza and respiratory syncytial virus infection in pediatric communities under the age of 18 years, the treatment of infants with the human monoclonal anti-respiratory syncytial virus antibody to prevent hospitalizations, most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, how the SARS-CoV-2/COVID-19 pandemic affected school attendance and child healthcare, how exposure length influenced transmission of SARS-CoV-2, how the durability of the anti-SARS-CoV-2 antibody response to protect against virus re-infection, if administration of oral antiviral therapy affected viral rebound in either the unvaccinated or vaccinated populations, as well as a reminder of the ineffectiveness of antibiotics for treating COVID-19 and the effect of vaccination on post-COVID conditions in children between 5-17 years old. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Pediatric outcomes SARS-CoV-2, flu, RSV (JAMA Peds.) SARS-CoV-2 vs Flu (Wired) Anti-RSV antibody treatment for infants (NEJM) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) COVID-19 school attendance (JPEIDS) COVID-19 pandemic effects children health care (JPEIDS) Digitally measuring transmission (Nat) Antibody titers and re-infection (CMI) Oral antiviral and SARS-CoV-2 rebound (MMWR) Rebound after antiviral controlled trial (MMWR) Vaccination and antiviral therapy (OFID) Antivirals and hospitalization (JMV) Antivirals molnupiravir (JMV) Convalescent plasma and the immunocompromised guidelines (IDSOciety) Steroid and the cytokine storm (OFID) Anticoagulation guidelines (hematology.org) Unnecessary antibiotics (NEJM) Vaccination and long COVID (OFID) RSV vaccination (MMWR) Antivirals and chronic kidney disease (CID) Early administraton of molnupiravir versus ritonavir-boosted nirmatrelvir (Lancet) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1074 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This Week in Virology, the Podcast About Viruses, the kind that make you sick.
0:07.0	From Microbe TV, this is Twive, this weekend virology, episode 1074, recorded on
0:19.7	December 28th, 2023.
0:23.0	I'm Vincent Dracken-yellow and you're listening to the podcast,
0:26.4	all about viruses.
0:28.5	Joining me today from New York, Daniel Griffin.
0:32.4	Hello, everyone.
0:34.0	Daniel it's our last clinical update for
0:37.0	2023 we've done 52 of them I guess 52 weeks right? Yeah you know that that is crazy we've done one we haven't missed we haven't missed since sometime in
0:50.2	February of 2020. That's right.
0:53.0	Wow.
0:54.0	And what have you got for a bow tie there, Daniel?
0:57.0	This is my anthrax bow tie.
1:00.0	One of my, I have more than one, can you believe that more, that more you know multiple one of my anthrax bow ties
1:05.9	You can't have too many anthrax bow ties in my opinion
1:10.0	Okay, that'll be a quotation for the future.
1:13.3	I got a list of them that go on the gravestone.
1:15.8	The guock is extra, you can not have enough, too many.
1:20.9	All right, let's jump into an actual quotation. For every complex problem, there's
1:26.7	an answer that is clear, simple, and wrong. And that's by Henry Lewis Menkin. And hopefully our listeners appreciate
1:38.0	that because there's so many clear simple and wrong answers out there. We have a lot to talk about this week. I'll share with
1:46.6	you, Vincent, because I'm also sharing with everyone, that I was on this last weekend
	...

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