TWiV 1062: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 18 November 2023

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses coverage with selected vaccines and exemption from school vaccine requirements among children in kindergarten, seasonality of endemic COVID-19, mRNA SARS-CoV-2 vaccination before vs during pregnancy and omicron infection among infants, extracting symptoms from free-text responses using ChatGPT among COVID-19 cases in Hong Kong, SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy, optimization of antiviral therapy in immunocompromised COVID-19 patients, a study to learn about the study medicines (nirmatrelvir plus ritonavir) in people aged 12 years or older with COVID-19 and a compromised immune system, evaluation of the safety profile and therapeutic efficacy of Remdesivir in children with SARS-CoV-2 infection, effect of neutralizing monoclonal antibody treatment on early trajectories of virologic and immunologic biomarkers in patients hospitalized with COVID-19, and SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Coverage with selected vaccines and exemption from school vaccine requirements among (CDC) Seasonality of endemic COVID-19 (Virology) mRNA SARS-CoV-2 vaccination before vs during pregnancy and Omicron infection among infants (JAMA) Extracting symptoms from responses using ChatGPT among COVID-19 cases (CMI) SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy (AIM) Optimization of antiviral therapy in immunocompromised COVID-19 patients (ClinicalTrials) A study to learn about nirmatrelvir/ritonavir in people with COVID-19 and a compromised immune system (ClinicalTrials) Evaluation of the safety profile and therapeutic efficacy of remdesivir in children with SARS-CoV-2 infection (EJP) Effect of neutralizing monoclonal antibody treatment on virologic and immunologic biomarkers in patients with COVID-19 (JID) SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy (AIM) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV on TWiV 1062 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	Are you curious about the present predicaments and future potential of science?
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0:43.8	Visit ASM.org slash books.
0:46.5	Type in the code think, that's THI-N-K to get 20% off your copy of thinking about science, good science, bad science, and how to make it better.
0:57.0	This week in virology, the podcast about viruses, the kind that make you sick.
1:07.0	From Micrope TV, this is Twive, this is Twive, This weekend, Vyrology, episode 1062, recorded on November 16,
1:19.4	2023. I'm Vincent Rachin-yellow and you're listening to the podcast all about viruses.
1:25.0	Joining me today here at the incubator in New York City, Daniel Griffin.
1:31.0	Hello everyone.
1:32.0	Good to have you back again, Daniel.
1:34.0	Yeah, it's nice to be spending some time.
1:36.0	After this, we're going to go to the Dixon-Day Pamee book signing.
1:40.0	That's very exciting.
1:41.0	Dixon should be in his element, right?
	...

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