TWiV 1038: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 26 August 2023

⏱️ 27 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses modeling poliovirus transmission and responses in New York State, FDA approves first vaccine for pregnant individuals to prevent RSV in infants, prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, Nirmatrelvir resistance – de novo E166V/L50V mutations in an immunocompromised patient treated with prolonged nirmatrelvir/ritonavir monotherapy leading to clinical and virological treatment failure, incidence of new-onset hypertension post–COVID-19: comparison with influenza, and post-acute sequelae of COVID-19 at 2 years. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Modeling poliovirus transmission and responses in New York State (JID) FDA approves first vaccine for pregnant individuals to prevent RSV in infants (FDA) Prevention and control of seasonal influenza with vaccines (CDC) De novo E166V/L50V mutations in an immunocompromised patient treated with nirmatrelvir/ritonavir (CID) Incidence of new-onset hypertension post–COVID-19 (Hypertension) Postacute sequelae of COVID-19 at 2 years (Nature Medicine) Contribute to our Floating Doctors fundraiser at PWB Letters read on TWiV 1038 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.4	From micro TV, this is TWIV, this week in virology, episode 1038, recorded on August 24, 2023.
0:22.4	I'm Vincent Drakaniello, and you're listening to the podcast, all about viruses.
0:28.1	Joining me today from somewhere, Daniel Griffin.
0:33.3	Hello, everyone. Yes, I am joining you from the mountains of Switzerland, a little town called,
0:40.2	well, going to pronounce it wrong, of course, but Moral, it's got the M, and it's got the U,
0:45.6	with the two dots, you know, the umlaut stuff going on, so I am certain I am mispronouncing it.
0:51.2	What are you doing there?
0:53.1	Well, I'm visiting my sister-in-law, my brother-in-law, there are three kids.
0:58.2	Oh, yeah, it's a bit of a family vacation, and I am not wearing a bowtie.
1:02.8	Yeah, you're chilling.
1:05.1	You jump in with my William Shakespeare quotation. Hopefully this will set the tone,
1:12.0	since gravity is the soul of wit and tediousness, the limbs and outward flourishes.
1:17.0	I will be brief, and so hopefully this will be one of our shorter episodes.
1:22.4	Well, definitely shorter when it comes to the COVID section, but I actually have quite a bit to talk
1:27.7	about with regard to a few other diseases. So polio, let me start with the MMWR progress
1:34.4	toward polio myelitis eradication, Pakistan, January 2022,
1:39.5	with Dash June 2023. Start with a little bit of background, since the establishment of the global
1:46.8	polio eradication initiative in 1988, Pakistan remains one of only two countries,
1:53.0	along with Afghanistan, with continued endemic transmission of wild polio virus.
1:59.4	So this report describes Pakistan's progress toward polio eradication
2:04.3	during this period, January 2022 through June 2023.
	...

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