TWiV 1014: Clinical update with Dr. Daniel Griffin

This Week in Virology

Vincent Racaniello

Vincent, Microbe, Medicine, Microbiology, Racaniello, Infection, Virus, Virology, Pathogen, Infectious, Twiv, Science & Medicine

4.8 • 2.2K Ratings

🗓️ 10 June 2023

⏱️ 40 minutes

🔗️ Recording | iTunes | RSS

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Summary

In his weekly clinical update, Dr. Griffin discusses estimates of SARS-CoV-2 seroprevalence and incidence of primary SARS-CoV-2 infections among blood donors, by COVID-19 vaccination status, smart thermometer–based participatory surveillance to discern the role of children in household viral transmission during the COVID-19 pandemic, COVID-19 vaccine mandates, changing severity and epidemiology of adults hospitalized with COVID-19 in the United States after introduction of COVID-19 vaccines, effectiveness of COVID-19 treatment with Nirmatrelvir–Ritonavir or Molnupiravir among U.S. veterans, national trends in anticoagulation therapy for COVID-19 hospitalized adults in the United States, development of a definition of postacute sequelae of SARS-CoV-2 infection, neuroinflammation after COVID-19 with persistent depressive and cognitive symptoms, long COVID clinical phenotypes up to six months after infection identified by latent class analysis of self-reported symptoms, and coronary microvascular health in symptomatic patients with prior COVID-19 infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Estimates of SARS-CoV-2 seroprevalence and incidence of infections among blood donors, by vaccination status (CDC) Smart thermometer–based surveillance to discern the role of children in household viral transmission during the COVID-19 pandemic (JAMA) COVID-19 vaccine mandates (GOV) Changing epidemiology of adults hospitalized with COVID-19 after introduction of vaccines (CID) Effectiveness of COVID-19 treatment with Nirmatrelvir–Ritonavir or Molnupiravir among U.S. Veterans (ACP Journals) National trends in Anticoagulation therapy for COVID-19 (IDSA) Development of a definition of postacute sequelae of SARS-CoV-2 infection (JAMA) Neuroinflammation after COVID-19 with depressive and cognitive symptoms (JAMA) Long COVID clinical phenotypes up to six months after infection identified by latent class analysis of self-reported symptoms (OFID) Coronary microvascular health in patients with prior COVID-19 infection (EACVI) Contribute to our FIMRC fundraiser at PWB Letters read on TWiV 1014 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]

Transcript

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0:00.0	This week in virology, the podcast about viruses, the kind that make you sick.
0:10.8	From micro TV, this is TWIV, this week in virology.
0:15.6	Episode 2014 recorded on June 8, 2023. I'm Vincent Drakin Yellow, and you're listening to the podcast
0:25.2	all about viruses joining me today from New York. Daniel Griffin. Hello everyone. How's the
0:33.6	air quality out there, Daniel? You know, that's been the topic of conversation. It was horrendous
0:40.3	yesterday, but I've been trying to get some kind of a sense, right? You know, like, so today it's
0:45.7	about half as horrendous as it was yesterday. My eyes have been tearing up, and I'm trying to figure
0:52.8	out, you know, we need a this week and just random things where we can ask someone.
0:59.2	You know, because they're like, it's really bad, but it's really bad. Like, is it like if I sped,
1:04.1	you know, two hours out sailing, is it like I smoked a cigar or a half cigarette or, you know,
1:09.2	I left some sort of quantification, but good question. It's not, I said, I'm my lane, Daniel.
1:14.3	It's not in my neither. So, you know, hey, email us please, because I'd love to be able to give
1:19.6	some context here. Today I'm wearing my HIV bow tie, and I will start right with my quotation.
1:26.6	Being honest may not get you a lot of friends, but it'll always get you the right ones. And that's
1:33.1	by John Lennon. Hmm. I will jump right into COVID. We'll start with the MMW are estimates of SARS-CoV-2,
1:42.8	zero prevalence and incidence of primary SARS-CoV-2 infections among blood donors by COVID-19
1:49.4	vaccination status in the United States, April 2021 through September 2022. I just came out June
1:56.3	second. Now, to estimate the incidence of infection and prevalence of infection or vaccination
2:03.2	induced antibodies or both data from a nationwide longitudinal cohort of blood donors was analyzed.
2:11.8	A lot of people have comments about how representative are those of everyone else. CDC in collaboration
2:18.5	with Bite Talent, American Red Cross, Creative Testing Solutions, and Westat established a nationwide
2:25.3	cohort of 142,758 blood donors in July 2021. The cohort included persons who had donated blood
	...

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