Tonight, the major cross-country storm on the move and threatening Thanksgiving travel for millions.

The powerful system sweeping across the country from California to Maine.

Up to three feet of snow in the west, changing over to a wintry mix in the Midwest, and by Thursday hitting the East Coast.

Will it be a Thanksgiving washout? Al Roker is here. Also, the major shortage in

air traffic control, just as holiday travel is expected to break records. Also, tonight, the major

breakthrough after more than a year of fighting, President Biden announcing Israel and Hezbollah

have agreed to a U.S. brokered ceasefire.

When will it take effect?

And what does it mean for the war against Hamas in Gaza?

President-Olank Trump vowing to hike tariffs on Mexico, Canada, and China on day one.

How those countries are responding and how will it impact the prices you pay?

The Biden administration

proposing drugs used for weight loss like OZempec, be covered by Medicare and Medicaid. More than

seven million Americans could benefit, but will the new Trump administration go along with it?

The warning if you're flying this holiday season, major airports being targeted

by car theft rings. And after the devastation from Hurricane Helene, the band marching on

to the biggest Thanksgiving celebration of them all. This is NBC Nightly News with Lester Holt.

Good evening and welcome.

Weather, which you can see, and FAA staffing shortages, which you can't see,

are complicating and maybe delaying many of your holiday travel plans tonight.

With record numbers of people on the move this holiday,

it doesn't take much to make things unravel.

...