Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Derek Christensen.

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All right, the drug of the day today is an eyedrop called Travaprost.

Brand name of this medication is Travitan Z.

This is probably the second most common eyedrop I see, at least in this classification.

First one being with Tannaprost.

I have done a previous podcast on that medication.

So if you want to go back through the archives and check that out, you certainly can.

So Travoprost is a prostate glandin analog, and it is used primarily for the treatment of glaucoma.

Essentially, what it does is it helps reduce intraocular pressure.

The exact mechanism, how that all works, it's a selective FP prostateanoid receptor agonist, which ultimately decreases that

intraocular pressure, which is the problem in glaucoma. It does that by increasing, essentially, the

fluid outflow, by decreasing resistance through the trabecular meshwork within the eye.

So that trabecular meshwork, that controls fluid flow, kind of pressure drainage out of the eye.

So that's how that drug primarily works. The dosing on this medication is very

similar to xylotan or latanopros. It's one drop every evening typically. With eyedrop administration,

I wanted to touch on that a little bit.

So first and foremost, if patients have contact lenses, they should remove them prior to giving the dose of medication.

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