Tranexamic Acid; time to treatment

The Resus Room

Simon Laing

Science, Emergencymedicine, Medicine, Health & Fitness, Em, Ae

4.8 • 678 Ratings

🗓️ 22 January 2018

⏱️ 12 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

In this episode we cover a paper that you have to know about!

The use of tranexamic acid(or TXA) has become widespread in the case of major trauma and post partum haemorrhage. This time we discuss a recent paper that asks us if giving it within 3 hours is enough, or whether we need to be even more specific regarding its urgency of administration in order to save lives from bleeding.

There is a superb podcast over at our buddies site PHEMCAST which covers an interview with one of the authors and we'd highly recommend listening to that!

Enjoy!

Simon & Rob

References

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Gayet-Ageron A. Lancet. 2017

Transcript

Click on a timestamp to play from that location

0:00.0	Welcome to the Recess Room podcast.
0:03.9	Five, four, three, two, one, fire.
0:13.0	So hi, and welcome back to the Recess Room podcast. I'm Simon Lang, and I'm Rob Fenwick.
0:17.9	And this is a podcast on a paper We weren't able to squeeze in
0:21.3	to January's papers of the month
0:22.5	But it's a biggie
0:23.6	And it's on the topic of TXA
0:26.4	Again
0:27.0	Again
0:27.7	So Rob
0:30.6	Crash 2
0:31.9	A massive trial
0:33.4	That I think has changed
0:34.4	All of our practice
0:35.8	Of care and trauma
0:37.0	So what was your take home from that study?
0:40.1	From crash to, my take home was that if you could get trinaxamic acid to your patient
0:46.0	within three hours of their injury and they had non-compressible hemorrhage, then they should
0:51.8	receive it.
0:52.6	And hopefully that would improve their
0:54.6	survival chances. I think that's probably pretty much what all of us took away from it, didn't we?
1:00.1	And there was this benefit, wasn't there, that was seen within three hours, and then there was
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Simon Laing, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Simon Laing and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.