Traces of Genetic Trauma Can Be Tweaked
Science Quickly
Scientific American
4.4 • 1.4K Ratings
🗓️ 15 April 2017
⏱️ 3 minutes
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| 0:00.0 | This is scientific Americans 60 second science. I'm Erica Barris. Got a minute? |
| 0:07.0 | In recent years, researchers have learned that trauma can be inherited, passed down due to changes in DNA, what's known as |
| 0:14.5 | epigenetics, but researchers recently uncovered a new wrinkle to the story. |
| 0:18.8 | The effects of trauma which can be transmitted to the offspring can be reversed by a positive |
| 0:26.2 | experience. |
| 0:27.2 | That's Isabel Manzu, professor of neuroepagenetics at the University of Zurich. |
| 0:32.0 | She and colleagues studied newborn male mice |
| 0:34.0 | and their mothers that were separated from each other, |
| 0:36.6 | which caused them both to experience traumatic stress. |
| 0:39.6 | Those male mice and their male offspring |
| 0:41.6 | display trauma symptoms symptoms which made them |
| 0:43.5 | different from other mice that had not been separated from their mothers. |
| 0:46.7 | But when these symptomatic mice were exposed to positive experiences, |
| 0:50.5 | their behavior changed, as did the fate of their offspring. |
| 0:55.0 | And we show that the negative consequences of this, which are depressive behaviors, |
| 1:00.0 | cognitive problems, antisocial behaviors, risk-taking. This can be reversed if the father, after being traumatized, was exposed to a positive environment. |
| 1:11.0 | So this reverses the symptoms and it also reverses the biological reason, |
| 1:17.2 | the biological cause for the symptoms in the progeny, which are the epigenetic marks. Epigenitic marks can |
| 1:22.4 | be corrected in sperm cells |
| 1:25.0 | by this positive experience. |
| 1:26.8 | The study was in the journal Neuropsychopharmacology. |
| 1:29.9 | Mansu says the behavioral changes |
... |
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