Top Neuroscientist: The Hidden Forces Making You Regain Weight (+ How To Beat Them)

The Liz Moody Podcast

Liz Moody

Self-improvement, Education, Mental Health, Health & Fitness

4.9 • 3.2K Ratings

🗓️ 25 March 2026

⏱️ 100 minutes

🔗️ Recording | iTunes | RSS

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Summary

Your brain is designed to regain weight you’ve lost. It is not a failure on your part—it is literally how your brain is wired. But it turns out, there are ways to outsmart it. This is the missing piece of weight loss that no one is talking about. In this episode, we get into why so many people struggle with losing weight and keeping it off longterm. The good news is, once you understand the science at play, there are tools you can use to finally break free, to rewire your brain so that you don’t need to white knuckle your way through life, and you can get the results you want and FEEL the way you want. My expert guest is Susan Peirce Thompson, a neuroscientist, professor, best-selling author, and the founder of Bright Line Eating. Wherever you’re starting, whatever you’re dealing with, this episode is going to give you hope and new information you won’t hear anywhere else. 🎧 What you’ll learn: • Why your brain is so resistant to losing weight and exactly what you can do about it • Why so many people regain weight after going off GLP-1s (and what you can do differently if you want to maintain your weight loss) • How to break through weight loss plateaus • The reason you get cravings and how to make them stop • 5 science backed ways to increase your willpower • Why you might want to STOP exercising if you want to lose weight Check out the previous episode of The Liz Moody Podcast discussed today: This Celeb-Beloved Therapy Offers A Radical New Way To Heal With Dr. Richard Schwartz Check out the resources mentioned in today’s episode: • https://www.foodaddictionquiz.com • https://www.jointhemaintenancemovement.com For more from Susan Peirce Thompson, Ph.D.: • Website: https://www.susanpeircethompson.com/ • Book, Maintain: https://www.jointhemaintenancemovement.com/#Order • Instagram: https://www.instagram.com/brightlineeating Ready to uplevel every part of your life? Order Liz’s book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now! Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome.Buy our cute sweatshirts, conversation cards, and more at https://shop.lizmoody.com/. Use our discount codes from our highly vetted and tested brand partners by visiting https://www.lizmoody.com/codes. To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. This episode is brought to you completely free thanks to the following podcast sponsors: • Puori: head over to Puori.com/LizMoody and use code LIZMOODY to get a discount and special offer. • Goodles: available nationwide at major grocery stores, Target, and Walmart or visit Goodles.com. • AG1: visit DrinkAG1.com/LizMoody and get a FREE bottle of Vitamin D3+K2 & 5 travel packs in your AG1 Welcome Kit with your first AG1 subscription order. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast. This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. The Liz Moody Podcast Episode 416. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	Your brain is designed to regain weight. It is not a failure on your part. It is literally how
0:05.9	your brain is wired. But it turns out there are ways to outsmart it. This is the missing piece
0:12.4	of the weight loss conversation that nobody is talking about. What we're getting into today is
0:17.6	why so many people struggle with losing weight and with keeping it off.
0:21.5	The good news is, once you understand the science at play, there are tools that you can use
0:26.1	to finally rewire your brain so that you don't need to white knuckle your way through life,
0:31.2	and you can get the results that you want and feel the way that you want to feel.
0:35.7	My guest today is Dr. Susan Pierce Thompson.
0:38.3	She is a neuroscientist.
0:39.3	She is a professor.
0:41.3	She is a best-selling author, and she is the founder of Bright Line Eating.
0:44.3	In this episode, we're going to get into the five science-backed ways to increase your willpower,
0:50.3	how to break through weight loss plateaus, the reason that you get cravings and how to make them
0:55.0	stop, and why your brain is so resistant to losing weight and exactly what you can do about that.
1:02.0	We're going to talk about why so many people regain weight after going off of GLP-1s and what
1:07.1	you can do differently if you want to maintain your weight loss. We're going to talk about why you might want to stop exercising. Yes, you heard that right,
1:14.5	if you want to lose weight. Wherever you're starting, whatever you're dealing with,
1:19.2	this episode is going to give you a lot of hope and a lot of information that you will not hear
1:24.0	anywhere else. Susan herself also has a crazy personal journey, both weight loss
1:29.1	and otherwise, which we will definitely be getting into. Welcome to the Liz Moody podcast
1:33.4	where we skip past the BS and get you actual solutions to your real problem so you can feel
1:38.2	as good as possible every single day. We're not going to tell you to just try harder. We're going
	...

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