Top 200 Drugs Podcast – Medications 91-95
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist
4.9 • 773 Ratings
🗓️ 10 October 2024
⏱️ 24 minutes
🧾️ Download transcript
Summary
On this episode of the Real Life Pharmacology Podcast, I cover 5 more medications of the top 200.
Fenofibrate is a medication used primarily to reduce triglycerides. This medication differs from statins which tend to focus on LDL management.
Doxazosin is an alpha-blocker. The primary indications of doxazosin are hypertension and BPH.
Naproxen is an NSAID. Of all the NSAIDs, naproxen is one of the lower-risk agents with regard to cardiovascular risk.
Spironolactone is an aldosterone antagonist and also classified as a potassium sparing diuretic.
Memantine is an NMDA antagonist that is indicated for the management of Alzheimer’s dementia.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
If you are looking for study materials and our list of popular Amazon books, check out meded101.com/store!
Transcript
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| 0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Derek Christensen. |
| 0:05.5 | Thank you so much for listening today. As always, go check out Real Life Pharmacology.com. I've got all |
| 0:11.7 | these medications more in-depth. If you're looking for a specific review on a medication, the drugs today |
| 0:20.3 | are going to be phenofibrate, doxazosin, neproxin, |
| 0:26.0 | spirulactone, and the last one we'll cover is memmintine. So again, I've tackled all these |
| 0:33.7 | medications individually and much longer, more detailed podcasts. So definitely go to |
| 0:39.1 | real life pharmacology.com, hit the podcast tab, and there should be a search bar on there where |
| 0:44.0 | you can search a specific medication and go back and listen to them in more detail. So take |
| 0:50.4 | advantage of that while you're at real life pharmacology.com. Definitely go check out the top |
| 0:55.9 | 200 medications PDF. It's a 31 page PDF on some of the most important things you're going to see in |
| 1:01.6 | practice as well as show up on your pharmacology and board exam. So definitely a no-brainer |
| 1:07.4 | to have for any healthcare professional or any aspiring healthcare professional. |
| 1:13.5 | All right, let's get into the medications today. We've got phenofibrate. |
| 1:18.4 | Brand name of this medication is tricor. There's a bunch of different brand name medications for this. |
| 1:26.3 | Trichore, lofibra, phenoglide, those are probably three of the more common ones that I've seen |
| 1:32.9 | utilized. |
| 1:34.6 | It is a fibrate derivative. |
| 1:38.6 | It's a medication used to lower cholesterol. |
| 1:42.5 | And mechanistically, its classification is a P. PAR agonist. |
| 1:48.5 | So what does that mean? |
| 1:50.5 | Phenofibrate is a paroxysome proliferator-activated receptor alpha agonist. |
| 1:58.8 | And that activation of P-par.R. Alpha increases lipolysis and ultimately the elimination of triglyceride rich particles from the plasma. |
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