Top 200 Drugs Podcast – Drugs 21-25
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist
4.9 • 773 Ratings
🗓️ 4 July 2024
⏱️ 14 minutes
🧾️ Download transcript
Summary
Lamotrigine is an antiseizure medication and also may be used for bipolar disorder. A rash is a major side effect to remember with this medication.
Valganciclovir is an antiviral medication that can be used to prevent cytomegalovirus (CMV) in patients with a suppressed immune system.
Fluconazole is an azole antifungal that can be used to treat candidiasis, blastomycosis, and tinea infections. Drug interactions, QTc prolongation, and hepatotoxicity are potential risks.
Atenolol is a beta-blocker used to treat atrial fibrillation and hypertension. It is relatively selective for beta-1 receptors meaning that it doesn’t affect the lungs as much as non-selective agents.
Montelukast is a medication that blocks the actions of leukotrienes. This can be beneficial for the management of allergies and asthma.
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Transcript
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| 0:00.0 | Hey all, welcome back to the real-life pharmacology podcast. I'm your host pharmacist, Eric Christensen. |
| 0:05.9 | Thank you so much for listening today. We are going to be continuing on with the top 200 drugs, |
| 0:12.9 | and I am on drugs number 21 through 25 today. And as a reminder, head on over to real-life pharmacology.com. Get your free PDF on the top |
| 0:25.7 | 200 drugs. Great study guide, great refresher. Lots of good clinical pearls, things you're going to |
| 0:32.3 | see in practice, as well as things that show up on board exams. So definitely a no-brainer. |
| 0:36.7 | Simply an email. We'll get |
| 0:38.1 | you access to that. And then we've got updates for you as well when we've got new podcast episodes |
| 0:43.7 | and other content available. All right. So number 21 is Valgang Cyclevere. Brand name of |
| 0:52.9 | this medication is Valcite. |
| 0:56.1 | And mechanistically, what this medication does is essentially blocks viral DNA synthesis. |
| 1:05.5 | It's actually a pro-drug. |
| 1:07.6 | Val-gang syclover is converted to Gansiclevare. |
| 1:13.3 | And probably the most common use I've seen this used for is CMV, prevention, prophylaxis, treatment. |
| 1:23.5 | So CMV stands for cytomyglovirus, and it is going to be most commonly associated with patients who are immunosuppressed. |
| 1:33.3 | So transplant patients, HIV-AIDS patients, they're at higher risk for this infection than patients who have a normally functioning immune system. |
| 1:49.5 | So adverse effects, boxed warnings, there are a bunch of boxed warnings that are associated with |
| 1:56.5 | valganiclyivir. |
| 1:59.7 | Hematologic toxicity, so that can be low white blood so cowl and low platelets, anemia. |
| 2:06.3 | It can actually impair fertility, so increase the potential for patients not being able to get |
| 2:13.7 | pregnant, things of that nature. |
| 2:16.1 | Fetal toxicity, birth defects can happen with this |
| 2:19.7 | medication as well. That is another boxed warning. And then there's cancer-associated risks as well |
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