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Well, I've got another special episode for you guys today on drug interactions. More

specifically, I'm going to take a look at my top 10 anticoagulant drug interaction. So, definitely

going to be touching on Pixaban, Warfarin, maybe even a little bit of lovinox and heparin. So plenty of drug interactions

here that you should know. Obviously, it's not an all-inclusive list, but it's some of the

most common things I've come across in practice, as well as maybe some of the most significant

things that you should be paying attention to with regard to anticoagulants.

So without further ado, here we go.

Number one, Apixaban, River Oxiban, these two agents have been certainly growing in popularity.

And it is recommended to avoid strong inducers of SIP 3A4 and peak glyca protein.

So Sip 3A4 is an enzyme that breaks this drug down.

Peak like a protein is a transporter that essentially helps get rid of drug, reduce concentrations.

And by inducing the action of these two things,

what you end up doing is lowering concentrations of apixaban or roxabam,

which ultimately increases the risk for blood clots,

...