5 • 716 Ratings
🗓️ 18 November 2021
⏱️ 13 minutes
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0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I am your host, pharmacist Eric Christensen. |
0:06.0 | Thank you so much for listening today. Go check out Real Life Pharmacology.com. |
0:12.3 | Snag your free download, 31 page PDF on the top 200 drugs. I throw out important clinical real-world pearls on that educational piece as well as things that you're going to see come up on board exams and pharmacology exams and things like that. |
0:29.5 | So a great refresher if you're in practice or if you're in school, definitely a helpful resource to help you study and prepare for any exams you might be facing there. |
0:41.6 | So with that said, let's get into the drug of the day today, and that is Tolteridine. |
0:48.7 | Brand name of this medication is detrol. |
0:52.2 | There is a detrol LA as well. That's a long-acting or extended release product. |
1:00.2 | This class of medication, or the class that Tultaridine belongs to is the anticholinergic class, |
1:07.1 | and more specifically, it's a urinary anticholinergic. |
1:12.2 | And the diagnosis that we're going to most often treat with this medication is overactive bladder. |
1:20.2 | So from a mechanism of action standpoint, |
1:24.2 | Tultoridine is relatively selective for the inhibition of muscarinic receptors in the bladder and urinary tract area. |
1:33.3 | So it can definitely help kind of retain that volume in the bladder, which is going to help you go to the bathroom less, right? |
1:46.1 | So reduce that frequency of urination. |
1:49.4 | That's the primary goal. |
1:50.7 | Reduce symptoms of overactive bladder and symptoms of frequency. |
1:55.8 | From a dosing perspective, we've got the immediate release, |
1:59.9 | two milligrams twice a day, and then the long |
2:02.9 | acting is four milligrams once a day. Obviously, that's an advantage typically to give a medication |
2:08.9 | once a day versus twice a day. In my experience, it has been a little bit cheaper to use the |
2:16.0 | immediate release, so you might see that. Another |
2:19.1 | situation that you might see the immediate released used is in patients maybe that just have |
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