Tobacco Plants Made to Produce Useful Compounds
Science Quickly
Scientific American
4.4 • 1.4K Ratings
🗓️ 15 July 2019
⏱️ 3 minutes
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| 0:00.0 | This is scientific American 60 Second Science. I'm Christine Herman. |
| 0:06.0 | Tobacco plants, of course, are grown to make cigarettes, but tobacco is also used a lot in scientific research. |
| 0:14.0 | And a new study shows tobacco can be genetically engineered to churn out large amounts of a commercially |
| 0:19.2 | important bacterial enzyme known as cellulase. |
| 0:22.4 | The enzyme has many industrial uses, including as an agent |
| 0:26.0 | in the production of biofuel. And even while their plant machinery is being co-opted |
| 0:30.8 | as an enzyme-making factory, the plants suffer no reduction in yield |
| 0:35.1 | while grown out in the field compared with unaltered plants. That fact is |
| 0:39.6 | rather remarkable because you might suspect that when a plant is expending resources to create large amounts of |
| 0:45.7 | cellulase it would struggle to grow. But that's not the case here. The proof of concept study is in the journal |
| 0:51.8 | Nature Plants. |
| 0:53.2 | University of Illinois Plant Biologist Justin McGrath is a co-lead author of the study. |
| 0:58.1 | He says the work could lead to lower costs for producing useful proteins like enzymes and some vaccines. |
| 1:04.8 | That's because it can be way cheaper to cultivate tobacco plants in a field |
| 1:09.2 | than to grow genetically modified yeast and other microbes indoors in large fermenters. |
| 1:14.2 | Here's McGrath. |
| 1:15.2 | Our estimates from this study are that it would cost between 20 cents and $1.1 to |
| 1:19.6 | produce a gram of the cellulase. |
| 1:21.9 | Whereas current methods, depending on the type of method |
| 1:24.7 | you're using, could cost from a couple hundred dollars to a couple thousand dollars. |
| 1:28.8 | Growing such plants in the field rather than indoors also makes it much easier to pursue really large-scale |
| 1:35.4 | production of medicinal and industrial proteins. But any time you talk about growing genetically |
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