5 • 716 Ratings
🗓️ 31 December 2020
⏱️ 14 minutes
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0:00.0 | Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen, |
0:06.9 | and I thank you so much for listening today. Hopefully you pick up a few clinical pearls along the way. |
0:14.2 | And of course, speaking of clinical pearls, go check out real-life pharmacology.com. And subscribe there, and I'll give you a 30 plus page PDF on the top 200 |
0:28.0 | drugs, kind of a unique little study guide that I personally put together where I lay out |
0:35.2 | important clinical pearls that you're going to see in clinical practice, |
0:40.2 | as well as things that commonly come up on board exams and things of that nature as well. |
0:46.6 | So if you've got anything to do with pharmacology, well, you're likely here for a reason. |
0:52.6 | So let's get into it with the drug of the day today. |
0:56.1 | And that is going to be teotropium. |
0:59.2 | And the brand name of this medication is Spireva. |
1:03.6 | Its primary use is in respiratory disorders. |
1:08.8 | More specifically, COPD. It's considered a long-acting anticholinergic |
1:17.4 | medication, also referred to as a long-acting muscarinic antagonist. Sometimes you'll hear the term |
1:27.1 | llama used as an acronym to kind of describe its classification. |
1:32.3 | And this drug works by essentially blocking acetycholine's action at muscarinic receptors, specifically M3 receptors or muscarinic three receptors. |
1:49.2 | And when acetylcholine binds those M3 receptors, what it leads to is bronchon constriction. |
1:59.2 | So basically that airway closing up. |
2:03.0 | And so if we prevent the cetocoline from binding those M3 receptors, |
2:10.7 | we can help cause the opposite, |
2:12.7 | which is broncholilation or that relaxation of the airway there, which obviously allows for better breathing. |
2:23.7 | Okay, so I said primary use is COPD. It can be used for asthma. It's typically a further down the |
2:31.8 | line type of medication in patients that aren't controlled |
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