Clausopine is the most effective medication we have for schizophrenia.

But how well it works depends on when you start it.

Welcome to the Carlet Psychiatry podcast, keeping psychiatry honest since 2003.

I'm Chris Aiken, the editor-in-chief of the Carlat's Psychiatry Report.

And I'm Kelly Newsom, a psychiatric MP and a dedicated reader of every issue.

Last month, we went to the Rapid Acting Mental Health Treatment Conference in San Francisco

with Owen Muir and Carline McMillan, who run the always fun and often cutting-edge frontier psychiatrist's

blog. The conference featured new technologies that aimed to treat and detect mental illness faster.

There was nightwear, an app that uses the Apple Watch to nudge people out of the dream state if they start

having nightmares, cleared by the FDA in 2020.

TD screen, an app that uses the smart frame camera to detect heart of dyskinesia.

And even one that is making clinicians' lives easier, including my own.

MD Hub.

It uses artificial intelligence to write your clinical notes for you by making a hippocomplying during the session.

And then there was Dr. Aiken, who didn't have a product to pitch, but was there to remind everyone that when it comes to mental health interventions, timing is everything.

Some of our listeners asked for a recording of the talk that I gave there, and we don't have one,

but I've turned it into this podcast series. And today, you're going to learn how timing matters was one of the most powerful treatments in our armamentarium, Clauseapine.

Experts may disagree on which antipsychotic to start with schizophrenia.

Some like Resperidol, or outside the US, a mazelpride.

Both of which have a large effect size.

Some choose chrypresine for its possible benefits in negative symptoms,

some like Alanzapine, which shines for its efficacy,

...