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The Human Upgrade: Biohacking for Longevity & Performance

This Legal Focus Powder Beats Any Dopamine Detox : 1352

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 26 October 2025

⏱️ 21 minutes

🧾️ Download transcript

Summary

Dopamine isn’t the enemy—low brain energy is. When your mitochondria can’t make enough ATP, your neurons misfire, leading to fatigue, brain fog, and lack of focus. In this video, I explain why dopamine problems are really energy problems, how mitochondrial health drives motivation and clarity, and why creatine is one of the most effective and affordable nootropics for restoring mental performance. Learn the biohacks that protect your brain’s power plants and keep you sharp all day long.


Chapters

0:00 – Introduction

0:22 – Brain energy vs dopamine

0:49 – ATP shortage causes fatigue

1:53 – Prefrontal cortex and energy

3:08 – Why ATP fuels focus and mood

4:40 – Stress, sleep and mitochondria

6:00 – Biohacks for energy production

7:39 – Backup battery: phosphagen system

8:46 – Creatine for brain energy & focus

13:18 – Vegans, women and creatine needs

15:07 – Best practices for dosing creatine

17:53 – Daily creatine + electrolytes


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Transcript

Click on a timestamp to play from that location

0:00.0

What if there was something you could add to your water to make you perform better, have more energy, and protect your cells from damage?

0:07.0

Hydrogen is the smallest molecule in the universe, and the only one that can get deep inside your cells, mitochondria, and even your DNA.

0:15.0

It fuels energy production, crushes oxidative stress, and supports sharper brain function.

0:20.0

Hydrogen's a gas so you can't take it as a pill,

0:23.4

so you either have to breathe it in or infuse it into your water. But your tap, bottled, or filtered

0:29.1

water doesn't have it. That's why I use the Echoflask. Echoflask is a hydrogen generator that

0:34.3

uses advanced electrolysis and a proprietary proton exchange membrane to

0:39.7

infuse your water with pure hydrogen. No chemicals, no pH change, just therapeutic science-backed

0:46.4

hydrogen. I've noticed more energy, faster recovery, less inflammation, and mental clarity that

0:52.5

lasts all day. Go to echo water.com slash Dave and use code

0:56.9

Dave10 for 10% off your echo flask. You'll feel the difference in days. The world is obsessed

1:05.1

with dopamine right now and for good reason. If you have good dopamine regulation, you care about doing things that matter in the world,

1:13.4

and that's a good thing.

1:14.4

It motivates you to pursue stuff that's important to you.

1:17.9

And every productivity expert right now says dopamine addiction is killing your focus, even though

1:22.8

dopamine's actually driving your focus.

1:24.7

You don't want to be addicted, but there's something else going on

1:27.7

underneath it. And you can do all this stuff like a dopamine detox, but you might not be getting

1:33.7

the results. You could say, I've got no apps all day, I'm eating a clean diet. Maybe you're just

1:40.0

having a cup or two of coffee instead of having coffee all day, but you're still tweaked and drained

1:44.8

by noon. What's going on? Maybe it has nothing to do with your dopamine levels. Maybe you have

1:52.3

a brain energy crisis, and when your brain doesn't have enough energy, it can't make enough

...

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