4.4 • 1.3K Ratings
🗓️ 17 July 2025
⏱️ 68 minutes
🧾️ Download transcript
Today’s show:
Jason and Alex tackle a full tech and business news docket on today’s show, including Jason’s big SF trip with Launch Accelerator’s 34th cohort, some peculiar social media posts from VC Geoff Lewis, a look inside the HUGE seed rounds being commanded by early-stage AI startups, crunching the numbers on how much compute data centers need to sell before they’re profitable, Polymarket asks who will be the next CEO of X and MUCH MUCH MORE.
Join us for the longest-running and most in-depth podcast on Earth for startup founders.
Timestamps:
(00:00) INTRO
(01:31) Jason’s in SF with LAUNCH Accelerator cohort 34… His take on the mood in Silicon Valley.
(07:52) Odd X posts from Bedrock Capital’s Geoff Lewis… what does it all mean?
(10:09) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist
(14:44) Ask JCal: What founders can do to guard their own mental health and well-being
(20:17) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(22:04) Thinking Machines Lab set a new record for a seed round: what’s going on with these MEGA deals?
(28:51) Alex (and Kabir from LAUNCH’s research team) investigated the economics of data centers… just HOW MUCH can you make from selling compute? And how long does it TAKE to turn a profit?
(30:52) Bolt - Don’t be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.
(37:09) Superintelligence vs. AGI: Jason thinks we’re still more than 2-3 years away…
(39:52) GPx is not a traditional VC fund: here’s what industry vet Brian Singerman is up to
(49:37) The importance of setting your own corporate culture… before it gets set for you!
(58:15) Polymarket has ideas for the next X CEO… see where Jason ranks on the list!
(01:03:18) Reddit wants to know… Do investors judge founders negatively who rely on lots of AI tools?
Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com
Check out the TWIST500: https://www.twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Lon:
Follow Alex:
LinkedIn: https://www.linkedin.com/in/alexwilhelm
Follow Jason:
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Thank you to our partners:
(10:09) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist
(20:17) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(30:52) Bolt - Don’t be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: https://substack.com/@calacanis
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com
Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Click on a timestamp to play from that location
0:00.0 | Can you think of a more challenging job than being the CEO of Twitter of X? I mean, oh my God, |
0:07.7 | it's like people are so full contact on there. It's, you know, if you have a freedom of speech |
0:15.3 | platform that is going to be that freedom of speech where people can really go for it. |
0:20.7 | You know, |
0:21.0 | Kanye West can go on an episode and say all kinds of crazy stuff. Like, I'm glad it's there, |
0:25.9 | but that means you have to come to work and deal with that. You know, and every day there's a |
0:32.9 | different Kanye West. This weekend startups is brought to you by Vanta. |
0:39.1 | Compliance and security shouldn't be a deal breaker for startups to win new business. |
0:43.7 | Vanta makes it easy for companies to get a SOC2 report fast. |
0:47.5 | Get $1,000 off for a limited time at vanta.com slash twist. |
0:54.1 | Northwest Registered Agent. Starting your business should be simple. |
0:58.5 | With Northwest Registered Agent, you can form your entire business identity in just 10 clicks |
1:03.7 | and 10 minutes. From LLCs to trademarks, domains to custom websites, they've got you covered. |
1:10.8 | Get more privacy, more options, |
1:13.0 | and more done. Visit northwest registeredagent.com slash twist today. And Bolt. Don't be left behind. |
1:22.9 | Build apps quickly without knowing how to code with bolt.new. Try it free at bolt.new slash twist. |
1:30.9 | Hey, everybody. Welcome back to this week in startups. I'm yours Jason Galicanas and with me, |
1:34.9 | Alex Wilhelm, my co-host. We've got a lot on the docket today. So I say we just jump right in. |
1:41.1 | How you doing there, Alex? I'm doing great. The biggest question on my mind, |
1:44.9 | Jason, is how goes the Silicon Valley trip? I know you're out there with the launch class of 34, |
1:49.3 | I believe. Yes, our 34th accelerator class, 10 companies, and we've done a couple of different |
1:56.5 | stops. And they've done wonderful. It's great to see so many founders with a couple of customers in that first year, |
... |
Transcript will be available on the free plan in 12 days. Upgrade to see the full transcript now.
Disclaimer: The podcast and artwork embedded on this page are from Jason Calacanis, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Jason Calacanis and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2025.