Hey all, welcome back to the real-life pharmacology podcast. I'm your host, pharmacist, Derek Christensen.

Thank you so much for listening today. Go check out real-life pharmacology.com. Get your free

31-page guide on the top 200 drugs. So definitely a no-brainer, great refresher. Or if you're going

through pharmacology classes, a great little

resource to have. I am also working on finishing up some free practice questions for nursing

pharmacology. So those will be available at real-life pharmacology.com very soon if they aren't already

by the time I release this podcast episode.

So pay attention to that and might be a little helpful for some of you going through

board exams and pharmacology classes throughout your health care career.

All right, with those announcements today, let's get into the drug of the day.

So the drug, I guess I'd classify it more so as a supplement today is thiamen.

This is vitamin B1, and a little bit of background about thiamine. The situation that I see it used most

in clinical practice are typically patients with alcohol use disorder. Excessive alcohol intake

can lead to significant thiamine deficiency.

Now, why is thiamine important?

So mechanistically, thiamin is a co-factor in carbohydrate metabolism.

If you remember your cycle in organic chemistry and things like that.

It helps out with the formation of ATP, which is a primary energy source for the body.

So obviously, if we don't have thiamen, that can definitely lead to some issues with that production and certainly some complications which I'll get into.

So uses of thiamine, thiamine deficiency is pretty much the only situation that's going to be

used in.

Again, Alco-use disorder, most common.

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