Check out our Sponsors Butcher Box: Ground beef for life is back! For a limited time, new members can get 2 pounds of free ground beef in every Butcher Box order by signing up today at ButcherBox.com/impact InsideTracker: Get 25% off their entire store at insidetracker.com/impacttheory Audible: Start listening with a 30-day free trial, one free audiobook and access to the Plus Catalog. Visit audible.com/IMPACT or text IMPACT to 500-500 Pharmaca: Go to Pharmaca.com/impact to save 20% off your first order. Are you dealing with mental fog most days, crashing in the afternoons and just blaming it on lack of sleep or stress? Cognitive decline is known to begin as early as your 30s and has become the accepted norm with aging, yet many of us don’t even recognize it at its onset. In this episode, international expert in neurodegenerative diseases, Dr. Dale Bredesen, talks with Tom about the reversibility of cognitive decline and Alzheimer’s disease. While Alzheimer’s disease is well known as a progressive disease impacting seniors, too many people are missing the opportunity to course correct and reverse the effects of cognitive decline leading to Alzheimer’s disease in their younger years. Dr. Bredesen explains simple ways for you to improve these conditions, avoid them altogether, and enhance your mental cognition. He discusses the importance of reducing toxins and exposes four factors that are largely responsible for the decline in optimal cognitive performance. Pre-order Dr. Bredesen’s Book “The First Survivors of Alzheimer’s” https://www.amazon.com/First-Survivors-Alzheimers-Patients-Recovered/dp/0593192427 SHOW NOTES: Alzheimer’s | Relationship between cognitive optimization and Alzheimer’s [1:17] Cognitive Supply & Demand | Factors that affect the brain’s plasticity network [2:38] Brain Assaults | Dr. Bredesen reveals the kind of assaults causing injury to your brain [6:10] Amyloid Plaque | Dr. Bredesen explains the role of amyloid plaque in Alzheimer’s [7:20] Brain Shrinkage | Dr. Bredesen explains the problem with the brain chronically shrinking [9:23] Alzheimer’s Subtypes | What’s destroying your brain and subtypes of Alzeheimer’s [10:10] Leaky Gut | The relationship between leaky gut, inflammation and cognitive decline [10:59] Insulin | Dr. Bredesen explains insulin resistance associated to cognitive decline [11:55] Alzheimer’s Survivors | Dr. Bredesen’s upcoming book about survivors of Alzheimer’s [15:53] Enhanced Cognition | Dr. Bredesen on enhancing normal cognition [17:01] Detox | Ways to get rid of toxins and who benefits from detoxing [18:15] How to Get Alzheimer’s | Dr. Bredesen discuss ways to give yourself Alzheimer's [22:28] Toxins Balanced | Dr. Bredesen explains the dynamic balance of toxins in your body. [24:52] Inflammation Free | How to flush out amyloid plaque, free of inflammation [31:05] Optimal Diet | Dr. Bredesen cautions the kind of protein and fats for optimal health [34:09] Omega-6 Warning | Dr. Bredesen warns of the danger with Omega-6 and healthy ratios [35:12] Keto-Flex Diet | Dr. Bredesen reveals what the Keto Flex 12-3 diet is [42:34] Testing Cognition | Dr. Bredesen talks about testing for systemic inflammation [45:52] QUOTES: “We all have a some degree of exposure to toxicity by the air we’re breathing, by the water we’re drinking, by the food we’re eating, [...] if you’re eating mercury filled seafood, if you’re not eating grass-fed beef, if you have a high carb diet, if you’re eating simple carbs. All of these things are contributing to a lesser than optimal outcome.” [17:30] “We are all living in a toxic world, that’s the problem [...] detoxification is not just for sick people” [21:08] “Many of us will avoid Alzheimer’s, but we’re still going to have suboptimal cognition.” [24:24] “You have a dynamic balance. You’re exposed to toxins all the time and you are metabolizing them, inactivating them, excreting them all the time.” [24:52] FOLLOW Dr. Dale Bredesen: Website: https://www.apollohealthco.com/dr-bredesen/ LinkedIn:https://www.linkedin.com/in/dale-bredesen-2ab0651/ Facebook: https://www.facebook.com/drdalebredesen/ Risk for Cognitive Decline Test - https://www.apollohealthco.com/cognoscopy/ Prevention and Brain Optimization - https://www.apollohealthco.com/solution/precode/