The Truth About Obesity, Diabetes, and New Weight Loss Drugs

American Glutton

Health & Fitness

4.9 • 3K Ratings

🗓️ 25 August 2025

⏱️ 78 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this episode of American Glutton, Ethan Suplee sits down with Dave Knapp, patient advocate and founder of the first patient-centric obesity medicine news platform. Dave shares his deeply personal journey with obesity and type 2 diabetes—from years of yo-yo dieting and keto struggles to discovering GLP-1 medications that changed his life.

Together, Ethan and Dave explore misconceptions about obesity, the emotional toll of weight loss, the rise of new medical treatments, and the importance of community in navigating these challenges. This honest, eye-opening conversation is filled with hard truths, hope, and inspiration for anyone on a health journey.

SHOW HIGHLIGHTS

00:02 – Welcome and introductions

01:18 – Living with diabetes and obesity

04:40 – Obesity as a chronic disease

08:29 – Misconceptions about type 2 diabetes

10:22 – High school struggles and keto beginnings

13:36 – Diagnosis and the wake-up call

15:51 – Year of keto and frustration

23:24 – Facing surgery and discovering new drugs

26:35 – Building a patient-driven platform

33:46 – Safety concerns and misconceptions

41:46 – Why people resist obesity medications

46:32 – Transfer addiction and mental health

52:06 – Long-term effects and unanswered questions

56:27 – Loose skin and hidden struggles of weight loss

01:00:39 – The misconceptions about rapid results

01:02:55 – Final reflections and gratitude

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Transcript

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1:03.9	I want to take one minute and talk to you about three things.
1:07.5	The first is substack.
1:09.2	I'm on substack.
1:10.5	I'm writing longer formed things and I'm having
1:12.4	incredible conversations with my subscribers. So check it out. Go to Ethan suplea.substack.com and
1:19.3	join in on the conversation. We want your voice heard there too. That's one. The second thing is
1:25.8	the prep deck. Do you have your prep deck?
1:28.1	The prep deck is an incredible tool that takes the guesswork out of meal planning.
1:32.7	I have diet fatigue.
	...

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