The Truth About Longevity with Dr. Eric Topol
Laugh Lines with Kim & Penn Holderness
Kim Holderness
4.9 • 3.4K Ratings
🗓️ 11 November 2025
⏱️ 63 minutes
🧾️ Download transcript
Summary
What’s the secret to living longer and better? (Spoiler: It’s not a cold plunge or protein popcorn.) In this episode, we sit down with the brilliant Dr. Eric Topol — cardiologist, scientist, and author of Super Agers — to separate fact from fiction in the world of longevity.
We learn that blood tests are getting really good, GLP-1 drugs show real promise, and to always call Dr. Topol before you buy something TikTok tells you to. We cover everything from protein myths, weighted vests, and saunas to tests that could one day prevent Alzheimer’s and cancer. Penn and I also cover sleep tips, landlines, and Max Headroom. (Gen Xers, you get it.)
We hope this episode leaves you smarter, calmer, and surprisingly optimistic about the future of aging. We love to hear from you, leave us a message at 323-364-3929 or write the show at podcast@theholdernessfamily.com. You can also watch our podcast on YouTube.
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Laugh Lines with Kim & Penn Holderness is an evolution of The Holderness Family Podcast, which began in 2018. Kim and Penn Holderness are award-winning online content creators known for their original music, song parodies, comedy sketches, and weekly podcasts. Their videos have resulted in over two billion views and over nine million followers since 2013. Penn and Kim are also authors of the New York Times Bestselling Books, ADHD Is Awesome: A Guide To (Mostly) Thriving With ADHD and All You Can Be With ADHD. They were also winners on The Amazing Race (Season 33) on CBS.
Laugh Lines is hosted and executive produced by Kim Holderness and Penn Holderness, with original music by Penn Holderness. Laugh Lines is also written and produced by Ann Marie Taepke, and edited and produced by Sam Allen. It is hosted by Acast. Thanks for listening!
Hosted on Acast. See acast.com/privacy for more information.
Transcript
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| 0:00.0 | Oh gosh. |
| 0:01.3 | Yeah. |
| 0:02.1 | This is ridiculous. This is totally ridiculous. So you're not talking about a landline. You're talking about a bat phone. I will say it is the first time we have left a discussion with a doctor when we've talked about Alzheimer's today. With smiles on our faces. That I feel hopeful. Yeah, we get older every day. Got more wrinkles. That's okay. Yeah, we're laughing when we age. |
| 0:22.7 | Life is like a comedy stage. |
| 0:26.4 | And that's what we got laugh lines. |
| 0:32.6 | Hey, everybody. |
| 0:33.1 | I'm Kim Holderness. |
| 0:33.7 | And I'm Penn Holderness. |
| 0:34.6 | We are so thrilled that you are joining us for this episode of |
| 0:37.8 | Laugh Lafflines. This one is going to be so good. But I will let you know that if you know who Max |
| 0:43.8 | Headroom is, welcome to the show. We are your people. Yeah. We have also received many notes recently |
| 0:52.1 | that your haircut penholderness looks like Max Head Hedrum. Yeah. Yeah. So I think we |
| 0:58.0 | should, you know, Sam, her favorite thing to do, our producer is to do more editing. So a superimposition |
| 1:03.6 | with him next to me like a split screen. Yeah. So if you're watching on YouTube, do you know who |
| 1:07.6 | Max Sedgroom is? No, okay. She's saying no. So if you know, it's like our little secret. |
| 1:13.0 | He was the first like AI robotic human being on MTV and he had glitches when he talked. |
| 1:19.6 | And I'm pretty sure he was part of a massive campaign for either Coke or Pepsi. |
| 1:23.7 | And he's like our first AI personality. |
| 1:27.3 | Yeah, he was. And he was like our first AI personality. Yeah, he was. He and he was, he very boxy, um, suit. If I remember |
| 1:33.1 | correctly. And really just, yeah, just really rocked our generation. Yeah. I thought you're going to say |
| 1:38.2 | like really handsome or something to try to make me feel better. But, no, yeah, handsome. Um, can I also say |
| 1:42.9 | something? Yes. Like, here's how, here's how you know that you're our people. If you're old enough that you find a sweater that you really like it and you wear it for three straight weeks without realizing it for a podcast, were your people too. Oh, my gosh. This is the third straight week. I really do like this sweater, but I'm not. He is wearing this for the third week. It's not like I'm just wearing it every day. I just like this sweater. |
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