So up guys, Derek, more platesmore dates.com. Today we're going to be talking about topical sarms

and their potential therapeutic applications for hair loss prevention. So this is something I've

touched on a handful of times in the past, but I've never made a dedicated video to it. And I've

already talked about the effects of oral sarums in terms of hair loss prevention

capacity, but I haven't really touched on the topical, which is a more recent idea that came

to mind earlier in the year. And I've seen it play out a few times anecdotally now through

personal acquaintances and friends and whatnot.

And basically, let me just elaborate the mechanism here before we delve into some of the more scientific stuff.

So basically, when you look at hair loss in its start to finish cascade of events,

basically the thing that mediates this follicular miniaturization, this,

you know, like mystery is essentially androgens. So the higher the androgen load in your body,

the more hair loss you're going to get more or less. So if you're hair loss prone,

you raise your androgen index or your androgen load via exogenous

androgens, you're going to have more hair loss.

Like this is why if you take anabolic steroids, it accelerates your hair loss.

This is why if you don't take anabolic steroids, your natural steroids are going to cause

hair loss, but just to a less severe extent than if you injected a bunch of Trenblone or a bunch of mastron or a bunch of whatever.

So the thing is, is with, let's just look at, you know, like standard treatments, like finasteroid

dutastrii.

So these work, they're not anti-androgens, but they work by reducing the amount of

androgens in your body.

So how does it do this? It inhibits the enzyme 5 alpha

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