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True Weird Stuff

The Terrordome

True Weird Stuff

Now! Media

History, Science, Documentary, Society & Culture

4.9655 Ratings

🗓️ 27 September 2025

⏱️ 82 minutes

🧾️ Download transcript

Summary

Today/s True Weird Stuff - The Terrordome

 

Holmesburg Prison in Philadelphia became notorious for unethical medical experiments conducted on inmates from the 1950s through the 1970s. Prisoners, many of them poor and Black, were lured into participating with small payments; doctors also lied to prisoners about the risks. Under dermatologist Albert Kligman, inmates were exposed to chemicals, viruses, asbestos, and other toxic chemicals that caused lifelong physical and psychological damage. The horrors of this institution are why Holmesburg Prison was given the nickname, "The Terrordome."
 

 

 

Transcript

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0:00.0

Hey there, true weirdos. We'd like to save a seat for you at the true weirdos table.

0:06.3

All you have to do to sign up is go to true weirdstuff.com, wait for the pop up that says sign up for updates, fill out the info, and you're in.

0:14.8

And some lucky weirdos chosen at random are going to win a true weird stuff very high quality hoodie fancy enough for wearing to a deposition

0:23.8

sturdy enough to wear for robbing a grave and i promise we won't spam you and after the episode we hope

0:32.1

you'll stick around because we've got more to the story a little, little conversation, some bloodthirsty stuff right after the episode.

0:42.5

It's a treatment for acne, a treatment for aging skin, a treatment for leukemia.

0:48.6

Patented in 1957 and on the market since 1962, it's called Truttonoan. And with more than two million

0:57.1

prescriptions filed every year, it's one of America's most popular drugs. She might know it better

1:03.4

by the name Retin A. Now, what you might not know is how the man who developed it and patented

1:10.2

Tritanoin, Dr. Albert Klegman, tested his new drug.

1:14.6

He was a dermatologist at the University of Pennsylvania, and his partner in the venture was another physician named Dr. James Fulton.

1:22.5

Fulton had battled severe acne as a teenager, and he was on fire to find a medication that would spare

1:29.5

others that same torment.

1:32.0

Trout to know in retinae, it's so commonplace now, so routine and regular and every day

1:38.4

that we just take for granted that this near miracle treatment for acne is widely available.

1:45.2

But once, it was new and unproven.

1:49.6

Would it work?

1:50.9

Was it safe?

1:52.7

Doctors Cleggman and Fulton needed to test their discovery.

1:57.0

How lucky for them that there just happened to be funding available from a government agency that specialized in turning a blind eye to unlawful experiments on human beings.

2:07.4

And even more convenient, they had a whole pool of test subjects, thousands of them, all in one place.

2:15.5

Scores of men, bare chested in the heat.

...

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