The Organic Acids Profile in Clinical Practice with Cat Simmons and Cass Nelson-Dooley
The Root Cause Medicine Podcast
Kate Kresge
4.8 • 581 Ratings
🗓️ 20 March 2025
⏱️ 45 minutes
🧾️ Download transcript
Summary
In today's episode of The Root Cause Medicine Podcast, Dr. Kate Kresge sits down with Cass Nelson-Dooley and Cat Simmons from Diagnostic Solutions Laboratory to explore the clinical applications of organic acids testing. You'll hear us discuss: • How urine testing may offer different insights into metabolism compared to blood tests • How urine tests may help identify patterns related to nutrient status without invasive testing • Exploring how neurotransmitter metabolites may relate to mood and brain health • Why organic acids testing may be a useful option for children, especially when blood draws are difficult Cat Simmons, MS, RD, CDCES is a clinical dietitian with a master's degree in metabolic physiology and integrated exercise science from Colorado State University. With over 15 years of experience in laboratory diagnostics, she has worked across blood, stool, and urine testing platforms. At Diagnostic Solutions Laboratory, she plays a key role in test development and practitioner education, particularly in making complex biochemical concepts accessible and clinically applicable. Her background in sports performance nutrition and metabolism uniquely positions her to help practitioners understand and implement organic acids testing in clinical practice. Cass Nelson-Dooley, MS, studied medicinal plants in the rain forests of Panama, in 2003 as a Fulbright Scholar, and then launched a career in science and natural medicine. She researched the pharmacology of medicinal plants at the University of Georgia and AptoTec, Inc, and then joined the innovators at Metametrix Clinical Laboratory, then Genova Diagnostics. She has over 18 years of experience teaching clinicians about integrative and functional laboratory results. At Diagnostic Solutions Laboratory, she analyzes metabolomics and gut microbiome tests and develops educational tools. Ms. Nelson-Dooley owns Health First Consulting, LLC, a medical writing, patient education, and consulting firm that serves the integrative and functional medicine industry. Ms. Nelson-Dooley is the author of Heal Your Oral Microbiome and has published case studies, book chapters, and journal articles about natural medicine, nutrition, and laboratory testing. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide
Transcript
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| 0:00.0 | Well, hello there. I'm Dr. Kate Creske, your host for today. Today we're covering a topic that I find really interesting and really promising organic acids testing. |
| 0:09.7 | Now, some people hear about urine metabolite testing, and they have a couple different reactions. If you're schooled in nutrition, you know that you can use it to measure nutrient deficiencies like B6. |
| 0:18.7 | If you are used to measuring hormone metabolites, this might ring a bell. |
| 0:21.6 | But there's actually 80 different metabolites in the organic acids panel from diagnostic solutions |
| 0:26.6 | that can provide a variety of insights into things like your cortisol levels, your mitochondrial health, |
| 0:32.6 | how your Krebs cycle is working, and more. |
| 0:34.6 | What I really love is that there's a robust amount of evidence to support every single biomarker that's in this panel. We've got two experts here today, Cass Nelson Doley and Kat Simmons, to talk to us about why and how we should think about using this test in practice. They're also teaching a six-week boot camp with us at Ruby University in just a few weeks, where if you're a practitioner, you can get your own organic assets test, test yourself, and then follow along for six weeks as you get amazing pre-recorded content so you can learn at your own speed, but then show up for a live Q&A with our two experts you're going to hear from soon and ask them all of your questions. If you've ever considered incorporating organic assets testing into your practice, this is a great way to make sure that |
| 1:10.9 | you're really well educated and that you're confident when you begin ordering it for your clients |
| 1:14.8 | and that you know exactly who to order it for and how to explain it to them when the results come back |
| 1:18.9 | to get them great clinical outcomes. Before we get started, though, I want to talk to you about |
| 1:23.0 | something that comes up pretty often on this podcast, and that, of course, is lab testing. |
| 1:28.4 | You see, |
| 1:33.2 | testing is one essential way to understand the root cause of an illness. If you're an integrative or functional medicine practitioner, chances are you're policing a ton of orders with a ton of |
| 1:38.6 | different labs. The root cause medicine podcast is created by Rupa Health. Rupa is the best way to order, manage, and track results from over 30 different labs in one |
| 1:48.7 | single place for free. |
| 1:50.8 | Thank goodness. |
| 1:51.8 | No need to create and log into multiple portals ever again. |
| 1:55.6 | If you're a practitioner, make sure you go sign up at RupaHealth.com to create your free |
| 1:59.6 | account today. |
| 2:02.5 | Now, let's start the show. |
| 2:09.7 | Kat Simmons and Katznelson Dooley, welcome to the Root Class Medicine podcast. |
| 2:11.1 | Thanks for having us. |
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