The mRNA Breakthrough That Changed Medicine Forever with Nobel Laureate Katalin Karikó

Into the Impossible With Brian Keating

Brian Keating

Science, Physics, Natural Sciences

4.7 • 1.1K Ratings

🗓️ 3 November 2024

⏱️ 64 minutes

🔗️ Recording | iTunes | RSS

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Summary

Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 What if the secret to saving millions of lives was hidden for years—overlooked, dismissed, and even rejected? That’s the story behind the groundbreaking mRNA technology used in COVID-19 vaccines. Today’s remarkable guest, Dr. Katalin Karikó—a Nobel laureate whose persistence and vision changed the course of medical history—shares how she overcame countless setbacks to drive one of the biggest breakthroughs in modern medicine. Discover how a humble butcher’s daughter from Hungary developed the foundation for the COVID-19 vaccine and why mRNA could hold the key to curing cancer and other deadly diseases. Tune in to learn more about the mRNA revolution that almost didn’t happen! Key Takeaways: 00:00:00 Intro 00:01:06 Origin of the Hungarian phrase “Marslahok” 00:02:11 Judging a book by its cover 00:05:40 The definition of life and extraterrestrial life 00:09:28 Katalin’s early life and scientific curiosity 00:18:00 Understanding RNA and mRNA 00:24:43 Development of the COVID vaccine 00:28:44 The COVID vaccine controversy 00:35:41 Overcoming adversity and advice for young scientists 00:54:10 The future of mRNA research and dealing with pandemics 01:01:08 What was Katalin wrong about? 01:02:15 Outro Additional resources: 📚 Get “Breaking Through: My Life in Science” by Dr. Katalin Karikó: https://a.co/d/cZjaFCw ➡️ Follow me on your fav platforms: ✖️ Twitter: https://twitter.com/DrBrianKeating 🔔 YouTube: https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list: https://briankeating.com/list ✍️ Check out my blog: https://briankeating.com/cosmic-musings/ 🎙️ Follow my podcast: https://briankeating.com/podcast Into the Impossible with Brian Keating is a podcast dedicated to all those who want to explore the universe within and beyond the known. Make sure to follow/subscribe so you never miss an episode! Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	Hey there, welcome to a phenomenal episode of the Into the Impossible podcast featuring my friend and Nobel laureate, Catalin Carico.
0:08.8	Catalan won the 2023 Nobel Prize in Medicine and Physiology for her research and collaboration in the invention of the COVID-19 vaccination.
0:18.8	Now, I know these are controversial, and indeed, we did speak about
0:21.6	the controversy, but Catalan is a fierce, unstoppable force in science. I just love talking to her.
0:28.5	And I know you will, too. Her insights are infectious, no pun intended. I want you to dive deep
0:33.6	into this episode and really take away the human spirit can never be defeated.
0:39.4	When you have such incredible intellects like Catalan, there's no telling where the human mind can take you.
0:51.0	Any sufficiently advanced technology is indistinguishable from magic.
0:57.6	Open the pod bay doors, pal.
0:59.8	Professor, nice to meet you in person.
1:01.7	Thank you so much for coming on the Into the Impossible podcast.
1:04.8	Thank you for inviting me.
1:06.3	It's a great thrill to have you here.
1:08.2	I want to start off with a question.
1:09.8	Maybe you know about this, but maybe you don't. In Hungarian, allegedly, there's a term, a phrase, which refers to
1:16.3	Hungarian people. And it's the, ah, Marge Lacoch. Have you heard of this phrase?
1:23.2	Yes. Can you explain it for the audience? I might not know what it means. So there were
1:27.0	famous Hungarians, and then they were about the same age, and they were
1:34.7	very advanced in physics and mathematics and so on, and they, you know, kind of named them,
1:42.2	you know, coming from the Mars.
1:44.8	Right. Allegedly, Leo know, coming from the Mars. Right.
1:45.5	Allegedly, Leo Salard, who lived here in La Jolla for some of his life, I think towards
	...

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