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The Dr. Hyman Show

The Mouth-Body Connection: How Oral Health Shapes Whole-Body Healing

The Dr. Hyman Show

Dr. Mark Hyman

Health & Fitness, Nutrition, Medicine

4.6 • 8.7K Ratings

🗓️ 27 October 2025

⏱️ 54 minutes

🧾️ Download transcript

Summary

Most people don’t realize that what happens in the mouth can ripple through the whole body. The balance of the oral microbiome—the community of bacteria living in our mouths—can either protect us or trigger widespread inflammation that affects the heart, joints, and brain. Hidden dental infections or mercury fillings can quietly drive fatigue, autoimmune issues, or dementia—and fixing the mouth often helps the rest of the body heal, too. The good news is that with simple steps like eating whole foods (often removing gluten), cleaning the mouth well, and breathing through the nose, we can protect both our smile and our overall health. When we care for the mouth as part of the body, lasting wellness becomes possible from the inside out. In this episode, Dr. Todd LePine, Dr. Elizabeth Boham, James Nestor, and I talk about how a healthy mouth microbiome is a key to whole-body wellness. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. James Nestor is an author and journalist who has written for Scientific American, Outside, The New York Times, and more. His book, Breath: The New Science of a Lost Art, was an instant New York Times and London Sunday Times bestseller. Breath explores how the human species has lost the ability to breathe properly—and how to get it back. Breath spent 18 weeks on the New York Times bestseller list in the first year of release, and will be translated into more than 30 languages. Breath was awarded the Best General Nonfiction Book of 2020 by the American Society of Journalists and Authors, and was nominated for Best Science Book of 2021 by the Royal Society. Nestor has spoken at Stanford Medical School, Yale School of Medicine, Harvard Medical School, The United Nations, Global Classroom, and appeared on more than 60 radio and television shows, including Fresh Air with Terry Gross, the Joe Rogan Show, and more. He lives and breathes in San Francisco. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:The Functional Medicine Approach To Oral Health Getting Rid of Cold Sores and Canker Sores The Power Of Breath As Medicine

Transcript

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0:00.0

Coming up on this episode of the Dr. Hyman Show.

0:02.7

And there's a lot of organisms that are in the mouth.

0:05.5

In fact, the oral organisms, and we have hundreds of oral organisms,

0:09.2

there's about a 45% concordance between the bacteria that we find in the mouth

0:13.7

and the bacteria that we find in the digestive tract.

0:16.4

And you can think of the whole body as being like a tube.

1:14.0

Magnesium is like the body's natural chill switch. It helps regulate stress, sleep, mood, and more. But most people are deficient. And most supplements don't give you the full spectrum. That's why I recommend magnesium breakthrough. The only formula with all seven forms of magnesium. Feel calmer, sleep better, and give your body what it's missing. Bioptimizers has increased their discount for my audience. Go to bioptimizers.com slash hymen and use code Hyman to get 15% off your order today. Before we jump into today's episode, I want to share a few ways you can go deeper on your health journey. While I wish I could work with everyone one-on-one, there just isn't enough time in the day, so I've built several tools to help you take control of your health. If you're looking for guidance, education, and community, check out my private membership, the Hyman Hive for live Q&A's exclusive content and direct connection. For real-time lab testing and personalized insights into your biology, visit Function Health. You can also explore my curated doctor-trusted supplements and health products at Dr.hyman.com.

1:15.2

And if you prefer to listen without any breaks, don't forget, you can enjoy every episode

1:19.3

of this podcast, Add Free with Hyman Plus.

1:21.9

Just open Apple Podcasts and tap Try Free to start your seven-day free trial.

1:26.7

The gut is sort of where everything starts and it can either lead you down the path of health

1:31.3

or it can lead you down the path of disease. And the beginning of the gut is the mouth.

1:35.6

So as you mentioned, you know, in medical school, we didn't learn anything about the mouth.

1:39.6

That was like for the dentist, you know, we'll just ignore that. And the dentist just basically stay in the mouth

1:44.9

and they don't really realize that there's a whole body connected to the mouth or some of the

1:48.8

dentist don't. And this is where I think a lot of both, you know, even functional medicine

1:55.9

physicians and dentists really miss the connection. So unless you're working with a holistic smart dentist or a functional medicine doctor

2:06.2

who's aware of the connection between the mouth and the gut and systemic immune system,

2:13.5

you're going to be missing a lot of things.

2:15.7

And as you mentioned before, you know, there are a host of conditions, including premature birth,

2:23.5

obesity, diabetes, cardiovascular disease, rheumatoly arthritis, inflammatory bowel disease,

2:30.5

and even dementia that are directly connected to poor oral health.

...

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