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Finding Genius Podcast

The Molecular Language of Parasites: Dr. Timothy Geary Explains Parasite Ecology

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 29 January 2020

⏱️ 43 minutes

🧾️ Download transcript

Summary

In order to create anti-parasitic medications like filariasis treatment, researchers like Dr. Geary study how parasites hide from their hosts. When you listen in to this discussion, you'll learn:

  • How parasites are closer in cell type to us than bacteria and why that makes them harder to kill.
  • Why the coevolution of humans and malaria has made it unique among parasites.
  • Why molecules that parasites release like micro RNAs may be the key to their ability to hide from their host and survive.

Dr. Timothy Geary serves as Chair in Parasite Biotechnology at McGill University and also has an appointment at Queen's University in Belfast. His background is in pharmacology, but he has developed a specialty in anti-parasitic medication discovery. This includes genomic work on the host-parasitic interface, especially for filariasis treatment and gastrointestinal nematode infections.

In this podcast, he explains several aspects of how parasites function and how vertebrates and arthropod vectors maintain the parasite's sometimes-complex lifecycle. Adaptive pressures affect parasites to the same extent as most animal life and Dr. Geary describes some interesting results of this such as the lower instance of immunological bowel diseases in regions where parasites are more common. 

He also helps differentiate parasitic nomenclature in a way that explains how and why many parasites can continue their life cycle so successfully. He catalogs the difference between single-celled protozoan parasites like the originators of toxoplasmosis and multi-celled nematode creatures.

Finally, he explains his work to understand how parasites go into "stealth mode" and why this may lead to better anti-parasitic medication and treatment.

Learn more about contacting Dr. Geary and find a list of his publications at https://www.mcgill.ca/parasitology/faculty/geary

Transcript

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0:00.0

You're listening to the Future Tech Podcast with Richard Jacobs.

0:09.0

Future Technologies such as Artificial Intelligence,

0:11.8

Stem Cells, 3D printing, gene editing,

0:14.6

Bitcoin, blockchain, the microbiome, quantum computing, virtual reality, and exploring space

0:21.0

are much closer than you might think.

0:23.0

In fact, many early versions of these technologies are in play right now,

0:27.0

and the companies that are using these technologies are the focus of this podcast.

0:31.0

My goal for you, the listener, is to learn from these

0:34.4

podcasts. You may very well learn something that may change the course of your life

0:38.2

for the better. Steer you towards a new career or give you insight into

0:42.4

addressing a thorny medical problem.

0:44.4

Remember, this podcast and its content is informational and nature only. No medical,

0:49.3

tax, legal, financial, or psychological advice is being given.

0:53.0

If you've enjoyed the podcast, please listen, subscribe, like, and tell your friends about it.

0:58.0

Thank you. Hello, this is Richard Jacobs with the Future Tech and Finally Genius podcast series.

1:10.0

I have Professor Timothy Geary, not Timothy Lery,

1:13.4

Timothy Gery.

1:14.7

He's at McGill University.

1:16.4

We're gonna be talking about his studies on

1:19.4

paracetology, parasites in general.

1:21.6

So Tim, thanks for coming.

1:23.0

Thanks, Rich. I should also point out that I have an appointment at Queens University in Belfast in Northern Ireland.

...

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