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Dr. Joseph Mercola - Take Control of Your Health

The Mind-Mouth Connection: How Oral Bacteria Impacts Your Brain

Dr. Joseph Mercola - Take Control of Your Health

Briana Mercola

Health & Fitness, Health, Alternative Health

4.61.5K Ratings

🗓️ 5 March 2025

⏱️ 13 minutes

🧾️ Download transcript

Summary

Story at-a-glance

  • Research found that higher levels of harmful bacteria (Prevotella intermedia) in the mouth are linked to cognitive impairment, while beneficial bacteria (Neisseria and Haemophilus) support better brain function
  • Nitric oxide production by beneficial oral bacteria plays a crucial role in maintaining blood flow to the brain. Nitrate-rich vegetables help boost the population of these healthy bacteria
  • People with the APOE4 gene show a distinct oral microbiome composition. Research shows they have lower levels of Neisseria bacteria and higher amounts of Prevotella, which is associated with increased dementia risk
  • Harmful oral bacteria have the ability to enter the bloodstream and cross the blood-brain barrier, leading to brain inflammation that results in cognitive decline
  • Maintaining oral health through proper diet, regular brushing and flossing, nose breathing, avoiding antibacterial mouthwash and practicing oil pulling are effective strategies against cognitive decline

Transcript

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0:00.0

Hello, and welcome to another episode of Dr. Mercola's Cellular Wisdom, the show where we explore the

0:04.7

tiny things inside us that somehow end up running the entire show. I'm Ethan Foster, your ever-curious

0:10.1

observer of the human condition, especially when that condition includes interesting bacteria.

0:14.6

And I'm Alara Sky here to drop clever one-liners and microbiome facts in equal measure. Welcome,

0:19.5

everyone. We're about to prove that what

0:21.4

happens in your mouth definitely doesn't stay in your mouth. That sounds suspiciously like a tagline

0:25.9

for a questionable horror movie, Alara. Attack of the microbes, they came from the mouth.

0:30.8

And in this episode, their sequel, microbes march on the brain. But let's stay rational. We're talking

0:36.4

about how the oral microbiome can influence

0:38.4

cognitive health and even the risk of dementia. Quite a leap from brush your teeth, or you'll get a

0:43.4

cavity, to brush your teeth or risk forgetting to feed your cat. I assume there's some actual

0:48.6

science behind it. Absolutely. It turns out that the mouth is sort of a microbial grand central

0:53.1

station, with trains of bacteria making pit stops in every nook and cranny.

0:56.0

Certain ones can benefit brain function, others, not so much.

1:00.0

So let's set the stage.

1:01.0

A recent discussion by Dr. Mercola highlights a study that zeroed in on the connection between oral bacteria, nitric oxide production, and the risk of cognitive decline.

1:10.0

Sounds like the kind of science that

1:11.5

proves flossing could be your new memory booster. Because if there's one thing we all want,

1:15.4

it's to be able to remember exactly how many times we never flossed. But jokes aside, the study

1:20.2

looked specifically at individuals over 50, checking saliva samples and seeing how different bacteria

1:25.1

levels correlated with brain performance. So it's not just about whether you have morning breath. It's which microbes are having

1:31.3

a little block party in your mouth. Some are beneficial, like Niceria and

...

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