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The Funk'tional Nutrition Podcast

The Link Between Histamine, Gut Health, and Immune System Dysregulation | Ep 348

The Funk'tional Nutrition Podcast

Erin Holt

Mental Health, Health & Fitness, Alternative Health, Nutrition

4.9759 Ratings

🗓️ 18 February 2025

⏱️ 46 minutes

🧾️ Download transcript

Summary

Autoimmune conditions are on the rise, and more people are turning to functional medicine for answers. One emerging factor in immune dysregulation is histamine intolerance, which can manifest in a range of symptoms from digestive issues to chronic inflammation. 

In this episode, we break down the connection between histamine, gut health, detoxification, and immune response. We also explore the impact of chronic stress, mold exposure, and complex treatment reactions—plus, a new training opportunity for practitioners looking to deepen their expertise.

In This Episode:

(05:37) Systems Biology & Histamines Overview

(06:24) Histamines and Immune Response

(12:48) Constipation and Detoxification Factors

(17:59) Navigating Root Cause Analysis Paths

(20:28) Chronic Stress Despite Resolution

(23:45) Addressing Challenges in Diagnosing Histamine Intolerance

(27:02) Reactions to Complex Treatment Protocols

(31:56) Beyond the Gut: Histamine Solutions

(37:10) Living with Mold: Challenges & Realities

(41:48) Coffee Enemas: Advanced Health Strategies

(44:06) Short-Term Low Histamine Diet Tip

FOR OUR FULL LIST OF LINKS + RESOURCES, HEAD TO: 

https://www.thefunktionalnutritionist.com/podcast/348-histamine-gut-health-and-immune-system-dysregulation

Check out The Funk’tional Nutritionist: Website | Instagram

Transcript

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0:00.0

I'm Erin Holt, and this is the Functional Nutrition Podcast, where we lean into intuitive

0:07.2

functional medicine. We look at how diet, our environment, our emotions, and our beliefs

0:12.5

all affect our physical health. This podcast is your full-bodied, well-rounded resource.

0:18.6

I've got over a decade of clinical experience and because of that,

0:22.2

I've got a major bone to pick with diet culture and the conventional health care model.

0:26.3

They're both failing so many of us. But functional medicine isn't the panacea that it's made out

0:31.5

to be either. We've got some work to do. And that's why creating a new model is my life's work.

0:38.7

I believe in the ripple effect. So I founded the Functional Nutrition Academy, a school and mentorship for practitioners

0:43.5

who want to do the same. This show is for you if you're looking for new ways of thinking about

0:48.6

your health and you're ready to be an active participant in your own healing. Please keep in mind

0:53.5

this podcast is created for educational purposes only and should never

0:57.1

be used as a replacement for medical diagnosis or treatment.

1:00.7

I would love for you to follow the show, rate, review, and share because you never know

1:05.4

whose life you might change.

1:06.7

And of course, keep coming back for more.

1:11.5

Okay, so something that we're seeing a big uptick in clinically is histamine issues.

1:18.3

So we're going to chat about what that looks like, how if you're a listener struggling

1:23.2

with some of these symptoms, how you might know that you have histamine issues.

1:25.6

And if you're a practitioner listening, kind of how we navigate this in practice. So, Rachel, when a client

1:32.0

comes to you, at what point do you start thinking it might be a histamine issue? Like, what are they

1:38.2

presenting with? So the classic symptoms are allergies, right? Runny nose, scratchy throat, watery eyes, maybe eczema and hives. Some of the less common symptoms that we can see are things like a really sensitive bladder, feeling like they have to pee all the time or maybe irritation around the bladder. Diary, nausea, acid reflux are some of those digestive symptoms that we can sometimes

2:01.8

see. Honestly, a lot of our clients come to us with digestive issues, so I'm not always thinking

...

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