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Science Weekly

The latest twist in a Canadian medical mystery

Science Weekly

The Guardian

Science

4.2938 Ratings

🗓️ 20 May 2025

⏱️ 19 minutes

🧾️ Download transcript

Summary

In March 2021, the Toronto-based reporter Leyland Cecco heard about a memo sent by New Brunswick health officials that warned about a possible unknown neurological syndrome thought to be affecting about 40 people. Since then the story has taken many twists and turns, most recently with a peer-reviewed study that concludes there is no mystery illness after all. Cecco tells Madeleine Finlay about the devastating symptoms that patients experienced, and why the research is unlikely to resolve the conflict over what has been causing them. Help support our independent journalism at theguardian.com/sciencepod

Transcript

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0:00.0

This is The Guardian.

0:11.4

I cover Canada for The Guardian and occasionally kind of stories pop up on our radar that seem like they're local stories.

0:19.1

And then you give them a bit of a pause and you look and you realize there might be something a bit more to it.

0:25.4

When Layland Checo came across a memo sent to health officials in the Canadian province

0:30.7

of New Brunswick, warning them to be on the lookout for an unknown brain illness, he was

0:36.7

intrigued. So I flagged that to my editor, and what we thought was maybe going to be a one-off story or one in which there was an answer, turned into what's been a multi-year, baffling, mysterious, and ultimately quite confusing investigation.

0:51.3

This was in 2021, but the story had actually begun a few years earlier.

0:59.3

A cluster of more than 40 patients had emerged, presenting with odd neurological symptoms.

1:06.4

They were suffering from hallucinations, they had the feeling of insects crawling on their skin,

1:12.3

they had trouble balancing, trouble with their speech, with their memory. It was a pretty

1:17.5

wide range of neurological challenges they were facing. For the neurologists seeing them,

1:23.8

there was no kind of neat basket you could put them in.

1:32.0

The doctors couldn't figure out what was going on.

1:36.6

It's actually like really hard to figure out what someone has if they have a neurological illness.

1:39.0

In the intervening years, the number of people that appear to fit the case description has continued to

1:45.5

stack up. And what's particularly strange and concerning is that several of the patients are

1:51.7

relatively young. Some are even in their 20s and 30s. This one woman needs to use Alexa to remind

1:59.0

her to shower and to eat because she said her

2:02.1

kind of a neurological decline is something that the doctor told her is closer to someone in their 80s.

2:06.9

There have been investigations, concerns about environmental contaminants, claims of cover-ups,

2:13.7

and many surprising twists and turns in the story.

2:19.9

It's left those affected and their families with more questions than answers.

...

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